According to a study published in Nature by an international team led by the University of California, San Diego, childhood exposure to the bacterial toxin colibactin could drive early-onset colorectal cancer (CRC). The first author is Marcos Díaz-Gay, PhD, head of the new Digital Genomics Group at the Spanish National Cancer Research Center (CNIO) in Madrid, … Read more
Editorial Note: These are some of the highlights of the guidelines without analysis or commentary. For more information, go directly to the guidelines by clicking the link in the reference. Updated guidelines on therapy of adult diffuse astrocytic and oligodendroglial tumors were published in April 2025 by the American Society of Clinical Oncology and the … Read more
Advanced Therapy Shows Promise for Difficult-to-Treat Leukemia Cases Table of Contents Advanced Therapy Shows Promise for Difficult-to-Treat Leukemia Cases The Evolution of Treatment for Ph+ ALL Extending Treatment Beyond Initial Induction: A New Analysis Impact on Long-Term Outcomes and Transplantation Safety Considerations and Future Directions Ponatinib Demonstrates Efficacy and Improved Safety Profile in Philadelphia Chromosome-Positive … Read more
Stories about humans waking up from cryosleep have dominated popular culture for decades in the Alien films, Cameron’s Avatar, and Nolan’s Interstellar. While these films are out there, space- and time-wise, we know the science exists offscreen. Globally, there are about 500 people in cryogenic preservation: 300 of them in the United States. Thousands more … Read more
Stories about humans waking up from cryosleep have dominated popular culture for decades in the Alien films, Cameron’s Avatar, and Nolan’s Interstellar. While these films are out there, space- and time-wise, we know the science exists offscreen. Globally, there are about 500 people in cryogenic preservation: 300 of them in the United States. Thousands more … Read more
The teratogenic risk of antiepileptic drugs (AEDs) has been a major concern in pharmacovigilance over the past several decades. However, neurodevelopmental and autism-related risks associated with these medications have gradually emerged. Although international registries provide information, they are not sufficiently comprehensive to fully assess the risks posed by many AEDs introduced in the past 20 … Read more
TOPLINE: Only 5% of patients with trauma experienced significant hypoxemia within the first 8 hours of care, with no difference observed between restrictive and liberal oxygen strategies. METHODOLOGY: This substudy of the randomized TRAUMOX2 trial included 60 adults with trauma injury (median age, 49 years; 75% men) who were randomly assigned to receive either a … Read more
Children of immigrants from India were more likely to develop atopic diseases if born in the United States or Canada than those who emigrated with their parents, according to new research published in The Journal of Allergy and Clinical Immunology: Global. Additionally, parents overall had lower rates of conditions like asthma and food allergies than … Read more
Archyde Expert Groups Advocate for Refined Approach to Diagnosing Indolent prostate Cancer May 8, 2025 Two leading international pathology societies are urging a shift in how indolent prostate cancers are detected and diagnosed, aiming to reduce overtreatment and improve patient outcomes. Teh Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP) recently … Read more
Illicit drug toxicity is an “escalating public health emergency” in Canada that significantly affects adolescents, yet pediatricians are ill prepared to manage it, new research suggested. A study of more than 1000 pediatricians in Canada who care for young people aged 12-18 years found that while close to 14% reported caring for at least one … Read more