A large US trial shows that the cumulative burden of alcohol over decades matters for colorectal cancer risk, with heavy lifelong drinking increasing danger and stopping alcohol linked to fewer early precancerous polyps. Study: Association of alcohol intake over the lifetime with colorectal adenoma and colorectal cancer risk in the Prostate, Lung, Colorectal, and Ovarian … Read more
Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide. The mutational landscape of CRC is well characterized, revealing key pathogenic genetic abnormalities that drive carcinogenesis (cancer development) and disease progression. Moreover, a step-wise colorectal carcinogenesis model has been proposed wherein … Read more
The American Gastroenterological Association (AGA) released a new clinical guideline making no recommendation – for or against – the use of computer-aided detection systems (CADe) in colonoscopy. A rigorous review of evidence showed that artificial intelligence-assisted technology helps identify colorectal polyps. However, its impact on preventing colorectal cancer – the third most common cancer worldwide … Read more