Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth

Even after inflammation resolves, colonic stem cells can retain a hidden molecular memory that increases the likelihood of later tumour growth, offering a new mechanistic link between chronic inflammatory disease and cancer risk. Study: Epigenetic memory of colitis promotes tumour growth. Image Credit: Antonio Marca / Shutterstock In a recent study published in the journal Nature, … Read more

Irish researchers developing new blood test for colorectal cancer 

Early-onset colorectal cancer is expected to be one of the leading causes of death for adults between the ages of 20 and 49 by 2030, unless cancer is caught at an earlier stage A simple, high-accuracy blood test may transform outcomes for patients with colorectal cancer (CRC), Irish scientists believe. Researchers from Trinity College Dublin, … Read more

Chronic inflammation leaves epigenetic scars that increase future cancer risk

Chronic inflammation can raise a person’s risk of cancer, and a new study reveals key details about how that might happen in the gut and points to better ways to identify and reduce risk. Scientists at the Broad Institute and Harvard University have revealed in mice that after colitis, or chronic intestinal inflammation, seemingly healed … Read more

High-dose curcumin fails to produce lasting gut microbiome changes in IBD patients

Even at pharmacological doses that flood the colon but barely enter the bloodstream, curcumin’s effects on the gut microbiome proved temporary, highlighting the remarkable resilience of the human microbial ecosystem. Study: Effect of curcumin on the gut microbiota of patients with ulcerative colitis, Crohn’s disease and healthy participants. Image Credit: Faizal Ramli / Shutterstock In … Read more

Screening helps detect colorectal cancer at an early stage

More cases of colorectal cancer are detected at an early stage with screening. This is according to new research based on data from over 278,000 60-year-olds, who were randomly selected to undergo one of two interventions or no screening at all (usual care). The study, which is a collaboration between Uppsala University and Karolinska Institutet, … Read more

Rural cancer patients benefit from local surgical care

Adults living in rural communities often travel long distances when seeking treatment for cancer, but distant travel may not always be necessary to receive high-quality surgical care, according to a new analysis published in the Journal of the American College of Surgeons (JACS). The analysis, focused on adults with colon or lung cancer living in … Read more

New genetic model reveals role of keratin 8 in colorectal cancer development

Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients. This novel model helps scientists better understand how the disease develops and supports the search for new treatments. Colorectal cancer is … Read more

Cancer Survival Rates: US & Italy Show Record Highs

Of True Martinella Five years after diagnosis, 70 percent of patients are alive, compared to 50… The post Cancer Survival Rates: US & Italy Show Record Highs appeared first on Archynetys. Source link

Exercise & Colon Cancer: A Powerful Treatment?

Of Elena Meli For the first time a clinical study shows that physical activity can reduce the risk of recurrence and mortality after a colorectal cancer. The effect… The post Exercise & Colon Cancer: A Powerful Treatment? appeared first on NewsyList. Source link

Exercise slashes risk of death in patients with colon cancer – study

Exercise slashes the risk of death in patients with colon cancer by more than a third, a trial has found. Physical activity could also prevent the disease from coming back, as well as lifting mood, reducing fatigue and boosting strength, according to researchers. Colon cancer develops in the part of the large intestine known as … Read more