‘Start doing this now’ to beat hay fever, says GP

Consider closing your windows when pollen levels are high (Image: Alamy/PA) With the dreaded hay fever season looming, many Britons are already stocking up on tissues and eye drops in preparation. We consulted several GPs to discover what measures can be taken now to stay ahead of increasing pollen levels, hopefully preventing weeks of sneezing, … Read more

High use of anticholinergic drugs linked to increased cardiovascular disease risk

People who use drugs with anticholinergic effects, including certain antidepressants, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease. This is shown in a new study from Karolinska Institutet published in BMC Medicine. Anticholinergic drugs reduce the effect of the neurotransmitter acetylcholine and are commonly prescribed to middle-aged and … Read more

Thermodynamic insights into histamine H1 receptor ligand binding

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide range of physiological processes and are the targets of more than 30% of currently marketed drugs. The histamine H1 receptor (H1R) is one such GPCR subtype that … Read more