Allergy-associated acute coronary syndrome without anaphylaxis in a prospective observational study

Prescott, S. L. et al. A global survey of changing patterns of food allergy burden in children. World Allergy Organ. J. 6, 21 (2013). Google Scholar  Janeway, C. A. Jr. et al. Immunobiology: The Immune System in Health and Disease 5th edn. (Garland Science, 2001). Google Scholar  Lippi, G., Cervellin, G. & Sanchis-Gomar, F. Immunoglobulin … Read more

Thermodynamic insights into histamine H1 receptor ligand binding

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide range of physiological processes and are the targets of more than 30% of currently marketed drugs. The histamine H1 receptor (H1R) is one such GPCR subtype that … Read more

Long-term proton pump inhibitor use not linked to stomach cancer

The long term use of proton pump inhibitors (PPIs), a class of drugs widely used to treat acid reflux and ulcers, may not be linked to any increased risk of developing gastric (stomach) cancer, finds a study of Nordic health data published by The BMJ today. This finding should offer relief for patients needing long term proton … Read more

Antihistamine shows promise for treating rare genetic liver disease

A common antihistamine may offer hope for patients with a rare genetic disease that can lead to severe liver damage and ultimately require transplantation, according to new research from Rutgers Health. The study in Cellular and Molecular Gastroenterology and Hepatology found that chlorcyclizine, a decades-old allergy medication, could potentially treat erythropoietic protoporphyria (EPP), a condition … Read more