In Latin America, efforts to implement preventive strategies, diagnostic tools, and personalized treatment for patients with rheumatic diseases often face significant barriers. However, there have been promising developments, many of which have been driven by the growing field of genomic medicine. One such initiative is the Ibero-American Research Consortium on the Genetics of Rheumatic Diseases … Read more
In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused by calcium pyrophosphate (CPP) crystal deposition in joints. The findings of this novel study in the Annals of the Rheumatic Diseases, … Read more
TOPLINE: Patients with Sjögren disease (SjD) had a 68% higher risk for overall malignancy than the general population, with hematologic malignancies contributing more to this elevated risk than solid tumors. Cancer accounted for 23.8% of deaths, with older age at diagnosis, smoking, lymphadenopathy, splenomegaly, and cryoglobulinemia identified as key predictors. METHODOLOGY: Researchers conducted a prospective … Read more
“`html BREAKING: John Mauceri‘s Cardiac Surgery Success BREAKING: John Mauceri’s Cardiac Surgery Success Award-winning conductor John Mauceri is back on stage after undergoing cardiac surgery to treat a… The post John Mauceri: Conductor Returns to Stage After Health Recovery appeared first on NewsyList. Source link
John Mauceri, an award-winning music conductor, author, and recording artist, is celebrating his return to the stage in better health following specialized cardiac surgery at NYU Langone Health to treat a rare and life-threatening heart condition. Maestro Mauceri’s illustrious career has taken him to the world’s most prestigious opera houses, symphony halls, Broadway stages and … Read more
Women who choose to stop treatment during pregnancy and breastfeeding are putting their health at risk, and have to weigh their desire to have children and breastfeed against a risk that we know very little about. In two ongoing clinical trials, researchers establish a new standard for human lactation studies that includes sampling of breast … Read more
TOPLINE: Recombinant zoster vaccine (RZV) had no significant effect on major adverse cardiovascular events; however, it reduced all-cause mortality in patients with immune-mediated inflammatory diseases receiving Janus kinase inhibitors. The mortality benefit was particularly notable in women and patients aged 65 years or older. METHODOLOGY: Researchers conducted a new user design study utilizing the TriNetX … Read more
TOPLINE: Zimlovisertib plus tofacitinib showed greater efficacy than tofacitinib alone in reducing Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) in patients with rheumatoid arthritis (RA), with a significant reduction observed at week 12. METHODOLOGY: This randomized, phase 2 study, conducted across 77 centers in 10 countries, aimed to evaluate the efficacy, safety, … Read more
New research shows an unintended and unfortunate side effect of common drugs. They can simply help viruses spread. Drugs are supposed to help us get rid of disease, or at least alleviate the symptoms of them. It is therefore particularly unfortunate when, on the contrary, the drugs can contribute to making us sicker. Many … Read more
Emerging data about benefits of the newer weight-loss drugs for some chronic skin conditions suggests their potential use in dermatology, as well as a role for dermatologists in obesity management. Glucagon like peptide 1 receptor agonist (GLP-1 RA) medications began as treatments for type 2 diabetes (T2D), then emerged as weight-loss drugs. The newer generation … Read more