Could Kids’ Gut Bacteria Trigger Young Colorectal Cancer?

According to a study published in Nature by an international team led by the University of California, San Diego, childhood exposure to the bacterial toxin colibactin could drive early-onset colorectal cancer (CRC). The first author is Marcos Díaz-Gay, PhD, head of the new Digital Genomics Group at the Spanish National Cancer Research Center (CNIO) in Madrid, … Read more

Cut the Clutter in Gynaecological Cancer Diagnosis

More than 60% of patients with cervical cancer and 30% of those with endometrial cancer are diagnosed at an advanced stage, when survival rates are lowest. Although intensifying screening may seem logical, unnecessary procedures can be harmful. Routine procedures such as ultrasound, though often considered harmless, can lead to poorly indicated hysteroscopies and unnecessary biopsies, … Read more

Independent Cancer Risk Predictors ID’d for Sjögren Disease

TOPLINE: Patients with Sjögren disease (SjD) had a 68% higher risk for overall malignancy than the general population, with hematologic malignancies contributing more to this elevated risk than solid tumors. Cancer accounted for 23.8% of deaths, with older age at diagnosis, smoking, lymphadenopathy, splenomegaly, and cryoglobulinemia identified as key predictors. METHODOLOGY: Researchers conducted a prospective … Read more

New Imaging Triples Dense Breast Cancer Detection

Supplemental imaging techniques could more than triple cancer detection in dense breasts compared with standard care alone, according to new research. The study, published in The Lancet, found that abbreviated magnetic resonance imaging (AB-MRI) and contrast-enhanced mammography (CEM) could help detect an additional 3500 breast cancer cases per year in the UK. Around 2.2 million … Read more

Vitamin D Supplementation Protects Telomeres in VITAL

This transcript has been edited for clarity.  This is Dr JoAnn Manson, professor of medicine at Harvard Medical School and Brigham and Women’s Hospital. I’d like to talk with you about a recent report in the American Journal of Clinical Nutrition that suggests vitamin D supplementation has a promising role in protecting telomeres and slowing … Read more

Does Weight Gain After Breast Cancer Affect Outcome?

Women who gain a more substantial amount of weight after being diagnosed with breast cancer face an increased risk of dying from the disease, according to findings from a new study. However, that higher mortality risk only appears to apply to women who are overweight or at a healthy weight before diagnosis, not to those who … Read more

Mixed Results for BC’s Opioid Standard for Noncancer Pain

An opioid prescribing practice standard for chronic noncancer pain (CNCP) was associated with accelerated declines in opioid doses and high-dose prescribing in British Columbia (BC) but also with more aggressive and inappropriate dose tapering, a new analysis showed. In addition, the standard resulted in restricted access to opioids for patients who may have benefited from … Read more

Home Self-Collection Equals Clinic Exam for HPV Screening

A self-collection (SC) device that could easily be used at home proved safe and accurate for cervical screening in the SELF-CERV prospective nonrandomized clinical trial, as reported in JAMA Network Open. Known as the Teal Wand, the device was recently approved by the US Food and Drug Administration (FDA) for home use. When compared with … Read more

A Rising Threat to Cancer Care

As Hurricane Helene approached western North Carolina, Martin Palmeri, MD, MBA, didn’t anticipate the storm would disrupt practice operations for more than a day or so. But the massive rainfall and flooding damage last September proved to be far more challenging. Despite best efforts by the 13-physician practice, basic treatments for most patients were interrupted … Read more

Many Early-Onset Cancers Increasing, Particularly in Women

Rates of certain cancers in the United States — including breast, colorectal, and thyroid cancers — increased between 2010 and 2019 among patients aged less than 50 years, while overall cancer incidence and mortality rates did not increase, a new study found.  Among the more than two million cases of early-onset cancer diagnosed during this … Read more