Decoding Healthy longevity: Who to Trust? Table of Contents Decoding Healthy longevity: Who to Trust? Decoding Healthy Longevity: who to Trust? The Evolving Role of Healthcare professionals The Challenge of Expertise navigating the Information Landscape Personalized Approaches to Longevity The Future of Longevity Expertise FAQ: Healthy longevity CITY — May 3, 2025 — The pursuit … Read more
Chui Ming Gemmy Cheung, MBBS | Image Credit: Duke NUS Medical School A recent post hoc analysis identified faricimab as exhibiting greater improvements in anatomic outcomes than aflibercept during the head-to-head testing phase of the TENAYA and LUCERNE trials in neovascular age-related macular degeneration (nAMD). TENAYA and LUCERNE were randomized, double-masked, non-inferiority trials across 271 … Read more
By pinpointing how neuroestrogen directly boosts appetite-suppressing receptors in the brain, scientists are laying the groundwork for precision therapies that could tackle obesity from within the central nervous system. Study: Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake. Image Credit: r.classen / Shutterstock A study led by researchers at the Fujita … Read more
Archyde Impaired Synaptic Pruning in Autism: Immune Cell Dysfunction Identified Table of Contents 1. Impaired Synaptic Pruning in Autism: Immune Cell Dysfunction Identified 2. The Role of synaptic Pruning in Brain Growth 3. Macrophages and Synaptic Clearance: A New Clue 4. CD209 Gene: A Potential Mediator 5. Implications for Future Therapies 6. Source: 7. Frequently … Read more
Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer’s, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain’s blood vessels. University of Connecticut researchers report in the April 16 issue of Science Advances that mutations in the TARDBP gene that reduce TDP-43 protein levels also impair the cells … Read more
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests. A growing body of research suggests that neurobiological changes, particularly abnormalities in dendritic spines, tiny protrusions on nerve cells where synapses form, may be a hallmark of ASD. … Read more
Background and goal: Many adults aged 65 and older never receive a cognitive check during regular primary care visits. This study assessed the feasibility and acceptability of implementing a digital cognitive assessment for Alzheimer disease and related dementias (ADRD) screening into primary care. Study approach: From June 2022 to May 2023, seven Indiana University Health … Read more
Andrew Agbaje, MD, MPH, PhD | Image Credit: LinkedIn A recent study conducted collaboratively between the US, Switzerland, Australia, Finland, and the UK indicated that high blood sugar and insulin resistance substantially increase the risk of heart failure in adolescents, particularly females.1 Heart failure often results from existing conditions, such as type 2 diabetes mellitus. … Read more
Archyde Mindfulness Therapy Shows Promise in Combating Opioid Addiction Published: April 30, 2025 17:51:33 UTC SAN DIEGO – A mindfulness-based therapy is showing potential as a weapon against the opioid crisis. Researchers at the University of California San Diego have discovered that Mindfulness-Oriented Recovery Enhancement (MORE) can effectively rewire the brain’s response to natural pleasures, … Read more
Researchers from the University of California San Diego have found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain’s response to natural healthy pleasure, leading to improved mood, greater attention to positive experiences and reduced opioid cravings. The findings, published on April 30, 2025 in the Journal of the American Medical Association (JAMA), suggest … Read more