World should focus on fighting tuberculosis – Opinion

LI MIN/CHINA DAILY US President Donald Trump”s spending freeze on foreign aid marks a significant challenge for the international development community, and many experts warn that diseases will surge. During these times of uncertainty about the future role of the world’s biggest donor, the Global Fund stands as a beacon of hope. Since the beginning … Read more

WHO urges immediate investment of resources to maintain tuberculosis care

On the occasion on World Tuberculosis (TB) Day, marked on 24 March, the World Health Organization (WHO) is calling for an urgent investment of resources to protect and maintain tuberculosis (TB) care and support services for people in need across regions and countries. TB remains the world’s deadliest infectious disease, responsible for over 1 million … Read more

Enhancing Bedaquiline with Curcumin for Effective M. abscessus Treatment

Archyde Curcumin and Bedaquiline: A Novel Combination Therapy Against Drug-Resistant Infections Table of Contents 1. Curcumin and Bedaquiline: A Novel Combination Therapy Against Drug-Resistant Infections 2. Fighting Back Against Antibiotic Resistance: A New Hope? 3. the Power of Synergy: Curcumin and Bedaquiline 4. Real-World Implications and Future Directions 5. Addressing Potential Counterarguments 6. Looking Ahead: … Read more

Adding curcumin boosts the efficacy of bedaquiline in combating M. abscessus infections

Mycobacterium abscessus is a fast-growing, pathogenic mycobacteria that can cause lung infections, and people who have respiratory conditions or are immunocompromised face a higher risk. It can also cause skin infections. The microbe is closely related to the one that causes tuberculosis and is naturally resistant to many antibiotics. Infections often require a year or … Read more

Researchers create mycobacteria with kill switches to improve TB vaccine safety

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with “kill switches” that can be triggered to stop the bacteria after they activate an immune response. Two preclinical studies, published, Jan. 10 in Nature Microbiology, tackle the challenge of engineering bacteria that are safe for use … Read more

Integrating health services to mitigate the shift in global aid – Academia

arlier this year, Indonesia’s health sector was subject to budget efficiency measures under a new presidential instruction to optimize government spending to support President Prabowo Subianto‘s priority programs. The sector now faces further strained resources, as… Source link

Groups push shorter treatment for children with tuberculosis

CHILDREN who have tuberculosis (TB) can be treated faster over the course of four months, according to new national guidelines adopted by the Department of Health (DOH) based on the recommendation of the World Health Organization (WHO). Doctors Without Borders (Medecins Sans Frontieres or MSF), which is supporting the Manila Health Department (MHD) and the … Read more

Haematological markers as predictive tools for tuberculosis in PLHIV: a retrospective cohort study in Gujarat, India | BMC Infectious Diseases

Our study demonstrates the potential utility of hematological parameters, particularly the monocyte-lymphocyte ratio (MLR) and anemia status, in predicting tuberculosis (TB) disease among people living with HIV (PLHIV). These findings contribute to a growing body of evidence supporting the use of readily available hematological markers in TB risk assessment and management in HIV-positive populations. Furthermore, … Read more

Prevalence, perception of risk and mycobacterium tuberculosis control practices among healthcare workers in HIV care and treatment centres in North Central Nigeria | BMC Infectious Diseases

HWs are often at an increased risk of developing infections due to their proximity to infected patients, and this risk is usually higher in high-risk settings [2, 9]. To this end, our study measured the perception of risk towards acquisition of TB and correlates this with the actual TB infection rates among HW working in … Read more

Multidrug-resistant TB in children is rising: Urgent global action needed

Despite global efforts, multidrug-resistant tuberculosis in children is rising at an alarming rate, with younger children at the highest risk of mortality—urgent action is needed to reverse the trend. Study: Global burden of multidrug-resistant tuberculosis in children and adolescents. Image Credit: Kateryna Kon / Shutterstock In a recent study published in the journal Pediatric Research, researchers leveraged … Read more