TOPLINE: Maintaining a healthy diet and a lower waist-to-hip ratio (WHR) throughout midlife was associated with improved brain health and cognitive function in older age in a new cohort study. METHODOLOGY: Researchers analyzed data from the Whitehall II Study (inception: 1985) at University College London, London, and the Whitehall II Imaging Substudy (2012-2016) at the … Read more
TOPLINE: Individuals with type 1 diabetes had more than twice the risk for ischaemic stroke and an 88% higher risk for haemorrhagic stroke than control individuals, whereas those with type 2 diabetes had a 37% higher risk for ischaemic stroke, with no significant impact on the risk for haemorrhagic stroke. METHODOLOGY: This Sweden-wide cohort study … Read more
TOPLINE: Among patients with acute cholecystitis who were managed non-operatively, 38.3% experienced new complications. Delayed cholecystectomy was recommended for younger patients with prior complications. METHODOLOGY: Researchers conducted a retrospective study to identify risk factors for gallstone disease relapse and establish the timeline for recurrence. They included 1634 patients treated for acute cholecystitis at three Swedish … Read more
TOPLINE: The albumin–bilirubin (ALBI) score predicted adverse outcomes such as preterm birth, intensive care unit (ICU) admission, and perinatal mortality in pregnant women with cirrhosis. METHODOLOGY: This prospective, national observational cohort study was conducted using the UK Obstetric Surveillance System (UKOSS) from June 1, 2017, to November 30, 2020. The study identified 52 pregnant women … Read more
Key Takeaways In cases of acute arthritis, it is crucial to consider infectious causes, particularly viral infections. This recommendation was made by a team of rheumatologists led by Dr Matthias Wahle, head and senior physician in the Department of Internal Medicine at University Hospital Augsburg, Augsburg, Germany, based on the case of a 59-year-old woman. … Read more
TOPLINE: Each 1°C increase in the mean daily temperature reduced the symptoms of depression by 0.2% but increased the symptoms of mania by 0.4% in patients with mood disorders, new research showed. METHODOLOGY: Researchers analysed data from 4000 adults (mean age, 30.9 years) with depressive symptoms and 2132 adults (mean age, 30.4 years) with manic … Read more
The French National Agency for the Safety of Medicines and Health Products has alerted healthcare professionals and parents about a concerning trend known as the “Paracetamol Challenge” that is gaining popularity, particularly on social media, among children and adolescents. This challenge involves the deliberate ingestion of toxic doses of paracetamol to evaluate one’s resistance and … Read more
Key Takeaways For men with genitourinary malignancies, such as prostate cancer, examining the external genital area is essential. While this may seem routine, it remains a crucial recommendation, as illustrated by the case of a patient reported by Portuguese physicians led by José Laert from the Department of Radiology, Hospital CUF Tejo, Lisbon, Portugal. The … Read more
anxiety, depression Significantly Worsen Outcomes for IBD Patients, Study Finds Table of Contents anxiety, depression Significantly Worsen Outcomes for IBD Patients, Study Finds IBD & Mental Health: The shocking link Between Anxiety, Depression, and Severe Inflammatory Bowel Disease Outcomes understanding the Complex IBD-Mental Health Connection Clinical Implications: Holistic Care is Crucial Looking Ahead: Future Research … Read more
TOPLINE: Among patients with active inflammatory bowel disease (IBD), those with both clinical and biochemical disease activity and two common mental disorders had a more than sixfold increased risk for adverse outcomes, including flares, glucocorticosterioid use, hospitalisations, and death. METHODOLOGY: Researchers assessed the impact of psychological comorbidity and disease activity on IBD prognosis in a … Read more