New study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types of cells. By systematically identifying thousands of rapidly evolving receptor-binding proteins, the researchers explain how these systems can be retargeted again and again in nature by swapping the part that binds to cells. The work not only … Read more
Bats, critical reservoirs of viruses with significant cross-species spillover risks, have long been understudied in the Indochina Peninsula. A study led by researchers from Beijing University of Chemical Technology, the Academy of Military Medical Sciences, and their partners has unveiled the region’s bat virome diversity, offering key insights into the origins of porcine epidemic diarrhea … Read more
Antimicrobial resistance – when bacteria and fungi defend themselves against the drugs design to kill them – is an urgent threat to global public health, according to the Centers for Disease Control and Prevention. To combat this threat, the Gerdt Lab at Indiana University Bloomington studies how to weaken bacteria’s defenses against viruses. “Bacteria get sick, … Read more
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex quasispecies populations, present a formidable obstacle to conventional molecular diagnostic approaches. Widely used methods such as reverse transcription quantitative polymerase chain reaction are highly susceptible to performance degradation when primer or probe binding sites accumulate nucleotide mismatches. … Read more
Implementation of health screening measures for passengers arriving in Bangkok [Getty] There is a low risk of the deadly Nipah virus spreading from India, the World Health Organization said on Friday, adding that it did not recommend travel or trade curbs after two infections reported by the South Asian nation. Hong Kong, Malaysia, Singapore, Thailand … Read more
HYDERABAD, India (Reuters) — There is a low risk of the deadly Nipah virus spreading from India, the World Health Organization said on Friday, adding that it did not recommend travel or trade curbs after two infections reported by the South Asian nation. Hong Kong, Malaysia, Singapore, Thailand and Vietnam are among the Asian locations … Read more
Recent reports of Nipah virus (NiV) infections in West Bengal, India, have reignited global concern, prompting public health authorities to prioritize research into this high-mortality pathogen. In response, Sino Biological, Inc., a global leader in recombinant technology, has announced the accelerated availability and development of critical research tools to support the global scientific community in … Read more
India has confirmed two cases of Nipah virus in West Bengal, a region in the eastern part of the country bordering Bangladesh, Bhutan, and Nepal. Both infected patients are healthcare workers from the region, and are hospitalised in intensive care. The Indian government added that 196 contacts of the confirmed cases are all asymptomatic and … Read more
A Purdue University team led by Kyle Cottrell has discovered a new therapeutic target for triple-negative breast cancer. “Triple-negative breast cancer is a particularly deadly form of breast cancer that currently lacks targeted therapies,” said Cottrell, an assistant professor of biochemistry. Cottrell, biochemistry graduate student Addison Young and their co-authors describe the discovery in the journal RNA. The … Read more
Background: Hepatitis C virus treatment is increasingly being offered in primary care because medications now require less frequent monitoring and have fewer adverse effects. However, many primary care clinicians still defer treatment to specialists due to administrative burdens, including laboratory workup, insurance prior authorizations, and pharmacy coordination, which can delay care. The innovation: At an … Read more