TOPLINE: Four clinical organizations jointly released a clinical advisory with evidence-based nutrition and lifestyle interventions to enhance glucagon-like peptide 1 (GLP-1) treatment outcomes for obesity. METHODOLOGY: An expert group comprised of multiple clinical and research disciplines assessed the literature to identify pragmatic priorities for nutrition and other lifestyle interventions relevant to GLP-1 treatment for obesity. … Read more
ORLANDO, Fla. — A program at Duke University School of Nursing, Durham, North Carolina, is currently one of just two in the United States that trains nurse practitioners (NPs) to provide endocrine specialty care, but more could be on the way. Established in 2016, the program was “a result of national demand for diabetes and … Read more
Orlando, Fla. — Fracture risk in people treated for obesity appears significantly lower with semaglutide (Wegovy) vs sleeve gastrectomy, new data suggest. Previous animal studies have suggested a dose-dependent effect of glucagon like peptide 1 (GLP-1) receptor agonists on trabecular bone, including increased osteoblast activity, reduced apoptosis, and suppressed osteoclast activity. However, human data have … Read more
TOPLINE: A substantial proportion of perimenopausal and menopausal women expressed willingness to undergo assessment for osteoporosis, especially among those of Chinese ethnicity and those with an older age, fracture history, and higher scores in perception of their osteoporosis risk. METHODOLOGY: Researchers conducted this cross-sectional study utilizing self-administered questionnaires to determine the factors that affect the … Read more
TOPLINE: Compared with a conventional ad libitum Mediterranean diet, an energy-restricted Mediterranean diet along with physical activity helped preserve bone mineral density (BMD) during weight loss in older women with metabolic syndrome, showing the most benefits at the lumbar level over a 3-year period. METHODOLOGY: Individuals with obesity and older adults exhibit increased vulnerability to … Read more
For many people, living longer brings health challenges: Osteoporosis, diabetes, Alzheimer’s disease. And of course, zombie cells. The technical term is senescent cells. They’re damaged and unable to repair themselves. They’re also more likely to linger in the body as we age — like zombies — secreting inflammatory molecules that can hasten our decline. “They … Read more
Belgian research scientist Clement Martin, who works with Belgium’s federal police to create a “perfume” that mimics the smell of dried human bones to help sniffer dogs find long lost remains, looks at human bones in his laboratory in Gembloux, Belgium January 15, 2025. | Photo Credit: Reuters A Belgian research scientist is working with … Read more
Women in early menopause treated with zoledronate in just two infusions, 5 years apart, show a significantly reduced risk of sustaining a vertebral fracture and better maintenance of bone mineral density (BMD) over a 10-year period than those receiving just one or no infusions over the period, suggesting the infrequent, early dosing to be a … Read more
Illustration inspired by Michelangelo’s The Creation of Adam. The central focus highlights a microCT scan of mouse bone repair at different stages: youthful bones (13:00), aged bones (22:00), and aged bones under an intermittent fasting protocol (18:00). Credit: Habib Lab, UNIL Intermittent fasting combined with localized Wnt3a treatments has been shown to rejuvenate bone repair … Read more