Radioactive treatment is among the first-line therapies used to effectively target and destroy cancer cells. But the same radiotherapy could also be a double-edged sword that ends up promoting the distant metastasis of tumours, a recent study has demonstrated. Radiation therapy is often used alone or in combination with surgery and chemotherapy to control the … Read more
In a global first, scientists have used advanced base editing to repair a deadly gene mutation in a newborn, marking a major leap forward in the treatment of rare inherited metabolic diseases. Study: Personalized Gene Editing to Treat an Inborn Error of Metabolism. Image Credit: Shutterstock AI Generator / Shutterstock.com In a recent New England Journal … Read more
Every living creature on Earth needs to protect itself from things that would do it harm. Bacteria are no different. And despite their relative simplicity, they deploy remarkably savvy defensive strategies against viral invaders. The most well-known is CRISPR-Cas9, adapted for human use as the first FDA-approved genetic editing technique. In the past year, researchers … Read more
Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results, recently published in Lancet Oncology, show encouraging signs of safety and potential effectiveness of the treatment. “Despite many advances in understanding the genomic drivers and other … Read more
Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the Greek word for bacteria-eaters, or in shortened form, “phages.” Scientists have sought to learn how the single-cell organisms survive phage infection in a bid to further understand human immunity and develop ways to combat diseases. Now, Johns … Read more
A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with researchers from Columbia University (New York, USA), has identified a mechanism that regulates the production of two different proteins from the same gene. This discovery, … Read more
Harnessing the Power of CRISPR in Regenerative Medicine: A Comprehensive Look In recent years, CRISPR/Cas9 technologies have emerged as groundbreaking tools in the rapidly evolving field of regenerative… The post Revolutionizing Regenerative Medicine: The Advancements and Potential of CRISPR Technologies in Tissue Repair and Disease Treatment appeared first on NewsyList. Source link
Study advances gene-editing capabilities for cancer and medical research through genetic manipulations using Cas12a enzyme Australian cancer researchers have been the first to establish a novel gene-editing tool for modelling and interrogating human disease. A pre-clinical model expressing an enhanced version of a new genome-engineering enzyme called Cas12a was generated by researchers at the Olivia … Read more
The search for gene therapies to treat rheumatoid arthritis (RA) has moved in fits and starts over the past two decades, with trials starting and stopping, and their focus shifting to osteoarthritis (OA). One gene therapy trial in OA is under way and another in RA is close to reaching human study, but that’s a … Read more
Researchers led by the University of California, San Francisco (UCSF), report a new approach that deprived tumors of nutrition in cancer models, and may one day lead to a new approach that can be further developed and personalized for specific cancers and patients. Their findings are published in Nature Biotechnology in an article titled, “Implantation … Read more