Eosinophils suppress tumor growth and recurrence in chordoma

Chordoma is a rare tumor characterized by poor prognosis, limited therapeutic options, and a high rate of recurrence. Despite advances in oncology, effective treatments for chordoma remain limited. Resistance to conventional radiotherapy and chemotherapy restricts therapeutic options, and surgical treatment is often challenging due to the tumor’s proximity to critical anatomical structures. Consequently, identifying novel … Read more

Blood lipid–hormone ratios predict future asthma attacks years in advance

Study: The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations. Image Credit: Prostock-studio / Shutterstock In a recent study in the journal Nature Communications, researchers analyzed medical records and blood samples from over 2,500 biobank participants with asthma to identify a novel predictive biomarker for future asthma exacerbations. The study used a metabolomics … Read more

Heavy smoking triggers systemic inflammation and vascular damage in new biomarker study

New research uncovers how heavy smoking rapidly disrupts blood and airway biology, revealing the hidden damage that accelerates disease risk in otherwise healthy adults. Study: The effects of heavy smoking on oxidative stress, inflammatory biomarkers, vascular dysfunction, and hematological indices. Image Credit: CGN089 / Shutterstock In a recent study in the journal Scientific Reports, researchers comprehensively evaluated … Read more