Ferlay, J. et al. Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018. Eur. J. Cancer 103, 356–387 (2018). Google Scholar Thorstenson, A. et al. Tumour characteristics and surgical treatment of renal cell carcinoma in Sweden 2005–2010: A population-based study from the national Swedish kidney cancer register. … Read more
Borrelle, S. B. et al. Predicted growth in plastic waste exceeds efforts to mitigate plastic pollution. Science 369, 1515–1518 (2020). Google Scholar Bao, L. et al. Incorporation of polylactic acid microplastics into the carbon cycle as a carbon source to remodel the endogenous metabolism of the gut. Proc. Natl. Acad. Sci. USA. 122, e2417104122 (2025). … Read more
A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This was discovered by researchers at the Rudolf Virchow Centre at the University of Würzburg. The human body cannot produce vitamin B2 – also known as riboflavin – itself; it must absorb the important substance through diet. The … Read more
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 inhibition offers an indirect strategy to counter KRAS-driven malignancy without direct KRAS targeting. Virtually all pancreatic ductal adenocarcinomas (PDACs) are initiated by activating mutations in the … Read more
Photoreceptors are specialized cells in the eye that convert light energy into neural signals. Several diseases… The post Photoreceptor Cell Death: Recovery Possible | [Your Brand/Site Name] appeared first on Archynetys. Source link
A novel approach to improving survival in treatment-resistant Cancers News-Medical Source link
The types of fats we consume directly impacts the survival and strength of the body’s immune cells and ability to fight disease, researchers have found. A University of Queensland team led an international collaboration that found diet could change the fat composition inside T cells – the immune cells that help protect a person from … Read more
Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years and may aggravate Alzheimer’s disease, according to a study from Cedars-Sinai. Published in Nature Communications, the discovery suggests this bacterium can amplify Alzheimer’s disease and points to potential interventions including inflammation-limiting therapies and early antibiotic treatment. The study … Read more
Chordoma is a rare tumor characterized by poor prognosis, limited therapeutic options, and a high rate of recurrence. Despite advances in oncology, effective treatments for chordoma remain limited. Resistance to conventional radiotherapy and chemotherapy restricts therapeutic options, and surgical treatment is often challenging due to the tumor’s proximity to critical anatomical structures. Consequently, identifying novel … Read more
Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in patients with aggressive inflammatory breast cancer. The study uncovers a novel role for soluble E-cadherin (sEcad) in promoting tumor invasion while resisting cancer cell death and triggering brain inflammation via the CXCR2 signaling pathway. The results … Read more