A new study sheds light on the behavior of yeast cells in the gut, paving the way for new lines of yeast that more efficiently produce therapeutic drugs tailored to address specific diseases. “Yeast is promising as a drug-delivery platform,” says Nathan Crook, corresponding author of the study and an associate professor of chemical and … Read more
Researchers at Washington University School of Medicine in St. Louis have received an $80 million grant to continue research into the mysteries of exceptional longevity. The grant renews support for the Long Life Family Study, a long-running, international investigation of multiple generations of families with unusually high numbers of individuals who have lived much longer than … Read more
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine’s (UMSOM) Institute for Genome Sciences … Read more
By The University of Melbourne’s Associate Professor Sarah Dunstan, Principal Research Fellow in Infectious Diseases and a Lead of the Global Health Cross-Cutting Discipline at the Doherty Institute Many people think leprosy is a disease of the past, yet around 200,000 new cases are reported globally each year. The ACCELERATE project, led by University of … Read more
Weill Cornell Medicine has received a $5.2 million, initial two-year award from the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics, and pHenotyping Technologies (LIGHT) program to develop a comprehensive and innovative approach to diagnosing lymphatic disease. LIGHT is led by ARPA-H Program Manager Kimberley Steele, M.D., Ph.D. The lymphatic system is a network of … Read more
When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity. A new study from researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center (MSK) provides fresh insights about how cancers evolve when they metastasize – insights that could aid in developing strategies … Read more
The “catastrophic” freeze on US funding for malaria has halted prevention programmes across Africa and also threatens to stall advances in genomic research, says Jane Carlton, director of the Johns Hopkins Malaria Research Institute. The US President’s Malaria Initiative (PMI) is one of numerous USAID-supported programmes to see its funding terminated under US President Donald Trump’s sweeping reforms this … Read more
Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children’s tumors and possibly opening up new or repurposed treatment options. Concentrating on a type of childhood kidney cancer, known as Wilms tumor, an international team genetically sequenced multiple tumors at a … Read more
A recent study involving 684 Chinese adults has uncovered a significant connection between gut microbiota, aging, and bone health, particularly in relation to osteoporosis, a condition that weakens bones and increases the risk of fractures. The research, conducted by BGI Genomics’ Institute of Intelligent Medical Research (IIMR) and partner institutions, was published in npj | Metabolic Health and Disease, an … Read more
Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease. Researchers at the Garvan Institute of Medical Research and UNSW Sydney have discovered why some people with celiac disease continue to suffer debilitating symptoms despite strictly avoiding gluten. The study, published in Science Translational Medicine, used cutting-edge single-cell … Read more