A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting carriers for imaging agents and therapies, opening a new route for safer drug delivery and vascular imaging. Study: In vivo metabolic tagging and targeting of circulating red blood cells. Image Credit: The1969 Studio / Shutterstock In a … Read more
HIV-1 can be neutralized by antibodies which bind to vulnerable structures on the virus surface. One such vulnerable site is the so-called V3 glycan site of the viral envelope protein. This target structure plays a central role in virus entry into human cells and has therefore long been an important focus for the development of … Read more
Targeted molecular interventions in the replication cycle and the immune recognition of viruses are intended to prevent viral entry into cells and virus replication. That is the goal of an international research project in which scientists work on new approaches to combating highly dangerous viral diseases such as yellow fever or Lassa fever. Coordinating the … Read more
Scientists uncover how the breakdown of a critical sugar-rich layer in brain blood vessels accelerates aging and disease—offering a new therapeutic target to restore brain health. Study: Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease. Image Credit: ART-ur / Shutterstock A recent study published in the journal Nature showed that the dysregulation of the brain endothelial … Read more