Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a Mayo Clinic–led study published in Cell Reports Medicine. The findings offer new insight into how the immune system and gut microbiome interact in this chronic condition and point to potential new therapeutic strategies. IBD, which includes … Read more
A sweeping analysis of nearly three million children pinpoints which early-life factors most strongly predict food allergy risk, revealing how skin barrier health, family history, and early exposures intersect to shape outcomes. Study: Risk Factors for the Development of Food Allergy in Infants and Children. Image credit: Alona Siniehina/Shutterstock.com A systematic review and meta-analysis of … Read more
The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single amino acid in this region transforms a full-length antibody into a stable half-IgG1 molecule with altered immune activity. The findings provide a … Read more
A first-of-its-kind clinical trial clinical trial shows that therapeutic plasma exchange (TPE) combined with intravenous immunoglobin reduced biological age on average by 2.6 years, as measured by multi-omic biomarkers. Results of the single-blind, placebo-controlled trial are published in the May 28, 2025, issue of Aging Cell, providing early data on the impact of TPE on … Read more
Feeding babies baked eggs early could prevent egg allergies—new research reveals how timing and exposure shape immune tolerance! Study: Tolerance to cooked egg in infants with risk factors for egg allergy after early introduction of baked egg. Image Credit: Dragana Gordic / Shutterstock A recent study finds that egg allergies in children can be prevented by introducing … Read more
Gut microbiota may be the key factor explaining why certain individuals do not respond well to the pneumococcal vaccine-a bacterium that can cause various diseases, such as pneumonia. This conclusion is drawn from a recent study led by the B Cell Biology Research Group at the Hospital del Mar Research Institute, published in Science Advances. … Read more
Scientists uncover how the breakdown of a critical sugar-rich layer in brain blood vessels accelerates aging and disease—offering a new therapeutic target to restore brain health. Study: Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease. Image Credit: ART-ur / Shutterstock A recent study published in the journal Nature showed that the dysregulation of the brain endothelial … Read more
Could antibiotics taken during pregnancy weaken the protective power of breast milk? A new study will explore whether prenatal antibiotic exposure reduces key immune factors in breast milk, potentially altering a newborn’s gut microbiome and immune resilience. Study Protocol: Effect of prenatal antibiotics on breast milk and neonatal IgA and microbiome: a case-control translational study … Read more
Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet. The blood test in this study (InFoods IBS, Biomerica) was specifically … Read more
Japanese Allergy Genes Unlock New Frontiers in Global Allergy Research Tokyo, Japan — A revolutionary study led by a consortium of international researchers has identified a unique genetic blueprint linked to allergic sensitization in both Japanese and European populations, marking a significant breakthrough in our understanding of this global health concern. The findings, published in … Read more