Physical function metrics improve mortality prediction in elderly heart failure patients

Current models of mortality risk after heart failure (HF) rely primarily on cardiac-specific clinical variables and may underestimate risk in elderly East Asian patients. Researchers from Japan used machine learning to analyze data from a nationwide registry of elderly HF patients. Their new model includes metrics of physical function and improved risk reclassification by about … Read more

Herpes virus infection softens cell nuclei through internal mechanical changes

A recent international research project has used advanced microscopy techniques and computational modeling to discover why virus infection changes the nuclear structures and biomechanical forces affecting the nucleus. Researchers at the University of Jyväskylä (Finland), in cooperation with national and international research groups, have shown that DNA viruses infect cells and take over the host … Read more

Microscopic structural changes in the aging heart may reduce risk of arrhythmias

Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC have discovered that microscopic structural changes in the aging heart may reduce the risk of irregular heartbeats. Medically known as arrhythmias, irregular heartbeats become more common with age and can lead to health problems. But a new study in JACC Clinical Electrophysiology, a journal of … Read more

Heart failure linked to faster cognitive decline

There are over six million Americans with heart failure who are at greater risk of losing their cognitive abilities earlier in life, a study suggests. The research team, led by Michigan Medicine, examined the cognitive abilities of nearly 30,000 adults over time, comparing those who did and did not develop heart failure. The researchers found heart … Read more

$2.17 million NIH grant awarded to investigate cranial osteopathic manipulation for brain injury recovery

Could applying a little pressure to the head be a game changer for the treatment of traumatic brain injury?  Virginia Tech’s Pamela VandeVord and Edward Via College of Osteopathic Medicine’s Gunnar Brolinson recently received a $2.17 million grant from the National Institutes of Health (NIH) to investigate how a technique called cranial osteopathic manual manipulation … Read more

EU project aims to combat dangerous viruses with molecular interventions

Targeted molecular interventions in the replication cycle and the immune recognition of viruses are intended to prevent viral entry into cells and virus replication. That is the goal of an international research project in which scientists work on new approaches to combating highly dangerous viral diseases such as yellow fever or Lassa fever. Coordinating the … Read more

Study explores microbiome reboot to prolong effect of Crohn’s disease therapy

A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn’s disease. Patients consume only this formula for six to eight weeks, completely avoiding solid foods. However, the exact reasons why this is helpful were previously unclear. Researchers at the Technical University of Munich (TUM) and the LMU University Hospital Munich … Read more

University of Oulu advances biosensor technology for disease detection

The University of Oulu is at the forefront of developing cutting-edge biosensor technology that could revolutionize the early diagnosis and treatment of diseases. The multidisciplinary research project, Next-Generation Molecular Sensors, led by Professor Caglar Elbuken, has secured nearly one million euros in funding from the Jane and Aatos Erkko Foundation to support a three-year research … Read more