Researchers at the University of Nottingham have developed a new genetic test that can diagnose brain tumours in as little as 2 hours The test, called ROBIN, uses PromethION nanopore sequencing to deliver rapid methylome classification. The researchers said results could be available intraoperatively, allowing clinicians to make faster, more informed decisions. The same assay … Read more
TOPLINE: In patients with metastatic breast cancer (BC), the prevalence of brain metastases increased with each treatment line, rising the most among patients with hormone receptor (HR)–negative, human epidermal growth factor receptor 2 (HER2)–positive disease and the least among those with HR-positive, HER2-negative disease. METHODOLOGY: Brain metastases indicate a poor prognosis in patients with metastatic … Read more
Incidence of preliminary cervical cancer decreased by approximately 80% among women aged 20-24 years in the United States since the widespread use of the human papillomavirus (HPV) vaccine, according to new data from the Centers for Disease Control and Prevention (CDC). The HPV vaccine was first recommended in 2006 for the prevention of cancers and … Read more
A physician-scientist at the University of Oklahoma is part of an international effort seeking new options for patients with head and neck cancer who cannot receive the standard chemotherapy drug cisplatin. Because cisplatin can damage the kidneys and cochlea, patients who have kidney problems or hearing loss are usually not candidates to take the drug. … Read more
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – known as the tertiary lymphoid structure – where they become frustratingly dysfunctional when in close contact with tumors. Described today in the journal Science Translational Medicine, … Read more
In a podcast episode, Digital creator Dr Austin Lake in conversation with an oncologist shed light on the fact that cancer patients are more likely to get oral infections. Curious, indianexpress.com spoke to a health expert and unearthed the connection. Dr Sandeep Goyle, Head of Medical Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai explained that oral … Read more
TOPLINE: In patients with ERBB2-positive metastatic breast cancer (ERBB2+ MBC) and brain metastasis, more than half of deaths were due to central nervous system (CNS)–related causes; however, patients with CNS-only metastasis have significantly longer overall survival than those with both CNS and extracranial metastasis. METHODOLOGY: About one third of patients with ERBB2+ MBC develop brain … Read more
New research, with the caveat of a relatively short follow-up, adds to encouraging data showing an overall low risk of the development of thyroid cancer associated with glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment. However, a notably increased rate of thyroid cancer detections limited only to the first year after drug initiation — but … Read more
In the largest study of its kind involving a diabetic population, the use of glucagon-like peptide 1 receptor agonist (GLP-1 RA) drugs shows no significantly increased risk for thyroid cancer, with the important caveat of the study’s relatively short follow-up period. “In this large multisite study utilizing data from 6 population-based databases, we found no … Read more
TOPLINE: Compared with standard concurrent chemoradiation, neoadjuvant chemotherapy followed by transoral robotic surgery (NECTORS) and neck dissection led to superior distant metastasis-free and overall survival outcomes in patients with advanced human papillomavirus–related oropharyngeal squamous cell carcinoma (HPV-OPSCC). METHODOLOGY: Distant metastasis is a leading cause of death in patients with HPV-OPSCC, and standard of care concurrent … Read more