Alzheimer’s-related brain changes progressed up to 20 times faster in women who also had abnormal levels of a Parkinson’s-related protein, according to a Mayo Clinic study published in JAMA Network Open. The same pattern was not observed in men. The findings suggest that when alpha-synuclein – a protein linked to Parkinson’s disease – accumulates alongside Alzheimer’s pathology, … Read more
Emerging evidence suggests widely used metabolic drugs could influence brain aging pathways, yet large clinical trials are still needed to confirm whether they truly alter the course of neurodegenerative disease. Study: The promise of GLP-1 receptor agonists for neurodegenerative diseases. Image Credit: Antonio Marca / Shutterstock In a recent review published in the Journal of Clinical … Read more
A new study by the University of Turku and Turku University Hospital, Finland, found that a significant proportion of Parkinson’s disease diagnoses are later corrected. Up to one in six diagnoses changed after ten years of follow-up, and the majority of new diagnoses were made within two years of the original diagnosis. A recent study … Read more
Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson’s disease in mice. Published in the open-access journal PLOS Biology on February 18th, the study shows that this metabolite is responsible for the formation of Lewy bodies and the death of … Read more