Among patients with overweight/obesity, a diet adapted to an individual’s chronotype was more effective in promoting weight loss and improving cardiometabolic health and gut microbiota (GM) than a conventional low-calorie diet. “Emerging evidence suggests that aligning dietary patterns with an individual’s circadian rhythm, or chronotype, may optimize metabolic processes and gut microbiota (GM) composition and … Read more
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TOPLINE: Parental metabolic syndrome (MetS) had a notable impact on the metabolic health of offspring; paternal MetS showed stronger associations with several metabolic markers in boys, whereas maternal MetS was linked to elevated triglyceride levels in both sexes but affected other markers, primarily in boys. METHODOLOGY: Multiple studies have examined the influence of parental MetS … Read more
ORLANDO, Fla. — A program at Duke University School of Nursing, Durham, North Carolina, is currently one of just two in the United States that trains nurse practitioners (NPs) to provide endocrine specialty care, but more could be on the way. Established in 2016, the program was “a result of national demand for diabetes and … Read more
TOPLINE: Metabolic syndrome was associated with a 24% increased risk for young-onset dementia, defined as dementia before the age of 65 years, with stronger associations found in women vs men, younger vs older adults, and individuals with vs without depression, a new study showed. METHODOLOGY: This nationwide population-based cohort study included data from more than … Read more
In women with signs of ischemia but no obstructive coronary artery disease (OCAD), intensive medical therapy did not reduce the first occurrence of a major cardiovascular event in the WARRIOR trial, but the trial was underpowered to show a definitive result. “This is a neutral trial and should not be considered a negative trial,” said … Read more
TOPLINE: Early introduction of atorvastatin vs placebo in patients with hypertension demonstrated significant benefits in reducing cardiovascular disease events, such as non-fatal myocardial infarction (MI) and coronary heart disease (CHD) events, over a 20-year follow-up period. METHODOLOGY: Researchers analysed data from the ASCOT lipid-lowering arm study and included 4605 UK participants with hypertension, at least … Read more
Wearable technologies such as smartwatches are providing physicians with new ways to monitor their patients’ health and detect cardiovascular risk factors. Metrics like daily step totals and average resting heart rate are already being used to predict cardiovascular health. Zhanlin Chen, a medical student at Northwestern University in Chicago, Illinois, however, has developed a new … Read more
TOPLINE: Switching from a boosted protease inhibitor (bPI)–based regimen to bictegravir plus emtricitabine plus tenofovir alafenamide (B/F/TAF) maintained virological suppression over 48 weeks in patients with HIV who had preexisting resistance to nucleoside reverse transcriptase inhibitors (NRTIs), however with increased adverse events. METHODOLOGY: This phase 4 trial assessed the safety and efficacy of switching from … Read more
Point-of-care (POC) testing can significantly increase routine lipid screening of preteen patients, according to findings from a study published in Pediatrics. At the beginning of the study, testing rates at three pediatric primary care sites in Pennsylvania were between 1% and 10% among preteens aged between 9 and 11 years, despite recommendations from the American … Read more