With congenital syphilis at a 30-year high in the US, experts stress that early and universal syphilis screening in pregnancy is vital to protect both mothers and newborns from preventable harm. Study: Screening for Syphilis Infection During Pregnancy: US Preventive Services Task Force Reaffirmation Recommendation Statement. Image Credit: Summit Art Creations / Shutterstock.com In a recent … Read more
Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow transplantation and regular cancer screening. But a new study demonstrates that mutations in one particular gene in the Fanconi anemia pathway result in an even … Read more
Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new research published in Blood Advances. “This is one of the first large, real-world, long-term studies to assess the efficacy of hydroxyurea outside of a controlled setting,” said study author Paul George, MD, … Read more
Luiz Felipe de Paiva Lourenção, Federal University of San Paulo | Image Credit: Linkedin A recent cross-sectional study conducted in Brazil indicated that the interaction of inflammation and iron deficiency could be triggering a substantial amount of anemia cases in children. Iron deficiency anemia has long been known to lead to eventual degradation of cognitive … Read more
Anne de Wit, MD | Image Credit: Linkedin A recent prospective subanalysis of an international open-labeled trial indicated that early detection and prevention of preoperative anemia is possible before colorectal surgery. However, preoperative iron administration cannot completely prevent postoperative complications, including colorectal anastomotic leakage (CAL). “Despite evidence indicating that preoperative anemia is a significant predictor … Read more
A recent retrospective analysis study indicated a correlation between preoperative anemia and likelihood of postoperative delirium (POD) in elderly patients after non-cardiac surgery.1 POD is a serious complication that affects up to 5% of general surgery patients, depending on type of surgery and patient population. POD is also increased with longer hospital or ICU stays, … Read more
Apr 10 2025 Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent. Due to overlapping morphological, clinical, and immunophenotypic characteristics, distinguishing these disorders from related entities such as T-prolymphocytic … Read more
Announcing a new article publication for Zoonoses journal. Hematologic disorders occur frequently in patients with Ebola virus disease (EVD) and are characterized by one or several abnormalities in blood cells, including hemostasis, which is poorly documented. This study described the hematologic abnormalities of Ebola patients and the impact on the outcomes of patients who were … Read more
A recent retrospective observational, nationwide register-based multicenter cohort study conducted in Italy revealed a trend of anemia in children with inflammatory bowel disease (IBD).1 Various studies have concluded that large percentages of children diagnosed with IBD worldwide simultaneously suffer from various forms of anemia. Relatively little research, however, has been conducted into the efficacy and … Read more
A machine learning model generated by a team from the European Society for Blood and Marrow Transplantation (EBMT) outperformed standard statistical models in identifying and stratifying transplant risk for patients with myelofibrosis, according to new research published today in Blood, the American Society of Hematology’s flagship journal. “Although there are many models available to identify … Read more