Novel bacteriophage offers a promising biocontrol solution against foodborne Salmonella

Researchers from China have identified a novel bacteriophage that offers a highly promising “green” biocontrol solution against foodborne Salmonella. The study was published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. This study was conducted to address the severe challenges posed by antimicrobial-resistant Salmonella to global food safety and public … Read more

Why Some Bacteria Survive Antibiotics

IntroductionResistance vs. persistence: Key differencesBiological mechanisms underlying persistenceClinical consequences of persistenceResearch advances and therapeutic strategiesReferencesFurther reading Antibiotic persistence helps a small subpopulation of bacteria survive treatment without becoming genetically resistant, often leading to relapse and prolonged infection. Researchers are uncovering how stress responses, metabolic slowdown, and biofilm-associated survival shape persistence and how these pathways could … Read more

Vaginal microbiome may play key role in pregnancy health and preterm birth risk, researchers say

Scientists reveal how shifts in the vaginal microbiome during pregnancy may influence inflammation and preterm birth risk, pointing to new microbiome-based therapies that could improve maternal and infant health outcomes. Study: The vaginal microbiome in pregnancy and preterm birth: mechanisms, disparities, and therapeutic opportunities. Image Credit: Kateryna Kon / Shutterstock In a recent review published … Read more

Specific gut bacteria may signal long-term risk of heart and metabolic disease

A large prospective study links specific gut microbes and diet-derived metabolites to future cardiometabolic disease risk, highlighting how the microbiome may reflect lifestyle factors shaping long-term heart health. Study: Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort. Image Credit: Anusorn Nakdee / Shutterstock In a recent study published … Read more

Comparing denture cleansers for effectiveness against Candida biofilms

Background and objectives Candida species, particularly Candida albicans, are major contributors to denture-induced stomatitis because of their ability to form biofilms on removable dental prostheses. Although chemical cleansers are effective, concerns regarding material degradation and mucosal irritation have spurred interest in non-chemical alternatives. This review aims to systematically compare the efficacy of chemical and non-chemical denture cleansers … Read more

CRISPR gene-drive technology reverses antibiotic resistance in bacteria

Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing number of “superbugs” have emerged, ramping up estimates of more than 10 million worldwide deaths per year by 2050. Scientists are looking to … Read more

Far-red light suppresses biofilm formation and virulence in pathogenic bacteria

Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for organisms ranging from single-celled bacteria to human beings. Some bacteria use photosynthesis to convert sunlight into energy just like plants, but other bacteria sense light for less well-known functions. In 2019, Sampriti Mukherjee, PhD, and … Read more

The Surprising Source of Next-Gen Antibiotics: Oyster Blood

The search for a solution to antimicrobial resistance found something. And researchers found it in a true “it’s always the last place you look” location. Australian oysters. Or more specifically, Australian oyster blood. We know antimicrobial resistance claims at least 1 million lives each year, and experts suspect that number to double by 2050. To … Read more