Even though older adults are more likely to be diagnosed with colorectal cancer (CRC), there is a concerning rise in diagnoses among younger adults, making it essential for healthcare providers to educate adult patients of all ages about the lifestyle-related risk factors associated with the disease. Many are familiar with the modifiable risk factors of … Read more
TOPLINE: Low-dose CT screening in a high-risk population detected lung cancer in 2.0% of participants, with nearly 80% of cases diagnosed at stage I or II. The screening protocol demonstrated 97.0% sensitivity at 12 months, with a 4.8% false-positive rate. METHODOLOGY: Annual low-dose CT screening has been recommended in the United States since 2013, but … Read more
BOSTON — Key DNA and chromosomal and immune cell changes in early-stage lung adenocarcinoma show significant associations with outcomes, representing potentially important early predictors to guide management of the increasingly prevalent, deadly disease, according to the results of a new study. “We found that DNA ploidy and chromosomal structure predict early recurrence in lung adenocarcinoma, … Read more
CHICAGO — Extended therapy with reduced-dose apixaban is just as effective as the high dose in preventing recurrent venous thromboembolism (VTE) in patients with active cancer who completed at least 6 months of anticoagulant treatment after a clot, and results in a lower rate of clinically relevant bleeding, the API-CAT trial shows. “Our results indicate … Read more
TOPLINE: A higher body mass index (BMI) across all ages as well as significant weight gain during adulthood were associated with a greater risk for renal cell carcinoma, while a BMI reduction of 10% or more in adulthood, especially after age 50 years, was associated with a lower risk for renal carcinoma, a new study … Read more
Two recent studies have added to the growing body of research suggesting consuming more dairy reduces a person’s risk of getting colorectal cancer. A prospective cohort study in Nature Communications published in January looked at the incidence of colorectal cancer (CRC) in more than 540,000 UK women over 16 years and found a 14% reduced … Read more
A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a crucial glycolytic enzyme, as a significant factor associated with lymphatic metastasis in HNSCC. HNSCC is an aggressive cancer with a relatively low 5-year overall survival … Read more
BOSTON — Patients with non-BRCA gene mutations undergoing risk-reduction surgery to prevent tubo-ovarian cancers showed no signs of tubo-ovarian high-grade serous carcinoma or serous tubal intraepithelial carcinoma compared with about 3% incidence of these carcinomas in patients with BRCA mutations in a multi-center study. “We need to define the role of risk-reduction surgery in reducing … Read more
Researchers have developed and internally validated a simple score using clinical factors that can help estimate the likelihood of advanced colorectal neoplasia in adults younger than age 45 years. While colorectal cancer (CRC) incidence has declined overall due to screening, early-onset CRC is on the rise, particularly in individuals younger than 45 years — an … Read more
Excess weight in mid-life is a known risk factor for kidney cancer, but new research indicates that weight patterns throughout life may also affect an individual’s likelihood of developing this malignancy. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. To assess weight patterns and their associations … Read more