Brain cancer is the second-leading cause of death in children in the developed world. For the children who survive, standard treatments have long-term impacts on their development and quality of life, particularly in small children and infants. Research out of Emory University and QIMR Berghofer Medical Research Institute in Queensland, Australia, has shown that a potential new targeted … Read more
CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient’s own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell. A major limitation of this type of CAR T cell therapy, called autologous therapy, … Read more
A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences. In the study, published Jan. 8 in the journal Nature … Read more
The cerebellum plays a critical role in both motor and non-motor functions, and its dysfunction is linked to various mental disorders, including autism. This study maps the three-dimensional distributions of 50,168 target neurons of cerebellar nuclei (CN) in wild-type and Nlgn3R451C mutant mice. The researchers found that the Nlgn3R451C mutation differentially affects projections from CN to the … Read more