Radial Access Problematic for Cerebral Angiography

A transradial approach (TRA) for cerebral angiography was less effective than the transfemoral route in achieving an accurate diagnostic success rate. Study investigator, Wei Ni, MD, Huashan Hospital, Fudan University, Shanghai, China, attributed the disappointing results to current equipment limitations in the current equipment transradial access. “Although we did not impose any restrictions on the … Read more

Epidural steroid injections may offer modest short-term pain relief for some back pain

The American Academy of Neurology (AAN) has developed a new systematic review to summarize for neurologists and other clinicians the evidence for epidural steroid injections and whether they reduce pain and disability for people with certain kinds of chronic back pain. The systematic review is published on February 12, 2025, online in Neurology®. It updates … Read more

Targeting PAK5 could offer new therapeutic approach for endometriosis

Endometriosis, a prevalent gynecological condition, is characterized by the growth of endometrial-like tissues outside the uterus, leading to severe pain and infertility in affected women. The pathogenesis of endometriosis remains elusive, and effective treatments are limited, highlighting the need for a deeper understanding of its molecular mechanisms. A pivotal role of P21-activated kinase 5 (PAK5) … Read more

Pain may lead to increased cigarette and cannabis use in cancer survivors

Experiencing pain may increase the odds that cancer survivors will use cigarettes and cannabis, according to a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. The study also found that cigarette smoking and pain are linked to more treatment-related side effects and worse health among cancer survivors. … Read more

Mediterranean diet boosts quality of life—here’s how

Discover how the Mediterranean diet not only enhances longevity but also strengthens mental resilience, physical health, and social well-being—offering a powerful strategy to improve quality of life at any age! Mediterranean Diet and Quality of Life in Adults: A Systematic Review. Image Credit: Spalnic / Shutterstock In a recent systematic review article in the journal Nutrients, researchers … Read more

Opioid δ-receptor Agonists Offer New Hope for IBS Treatment

A New Dawn for IBS Treatment: Targeting the Brain for relief Irritable bowel syndrome (IBS) affects over 10% of the global population, causing meaningful discomfort and impacting quality of life. While current treatments primarily focus on symptom management, a groundbreaking study published in the British Journal of Pharmacology offers a glimmer of hope: targeting the … Read more

New Drug Class May Help Alleviate IBS Symptoms by Targeting the Central Nervous System

Archyde Could Opioid Drugs Offer Relief for Irritable bowel Syndrome? Table of Contents 1. Could Opioid Drugs Offer Relief for Irritable bowel Syndrome? 2. Could DOP agonists Offer Lasting Relief for IBS? 3. A New Approach to IBS Treatment 4. Understanding the brain-Gut Connection 5. Targeting the Insular Cortex 6. Promising Future for IBS Patients … Read more

New drug class may help alleviate IBS symptoms by targeting the central nervous system

Irritable bowel syndrome (IBS) is a common digestive disorder that affects the intestine, causing symptoms such as abdominal pain, bloating, gas, and changes in bowel habits, including diarrhea, constipation, or both. Although this condition affects about a tenth of the global population, the underlying causes and mechanisms of IBS remain unclear. Consequently, treatments for IBS … Read more

New Guidance Aims to Reduce Surgical Infections

New guidelines from the American Society of Regional and Anesthesia (ASRA) Pain Medicine offer strategies for anesthesiologists and pain physicians to prevent infections that develop after surgery and other pain procedures. Surgical site infections (SSIs) — which by some estimates occur 500,000 times annually in the United States— increase hospital costs by more than $20,000 … Read more

Neonatal care survey shows inadequate pain relief for premature babies

A large proportion of babies born very early need intensive care, which can be painful. But the healthcare system fails to provide pain relief to the full extent. This is shown by the largest survey to date of pain in neonatal care, now published in the journal Pain. Every day for 4.5 years, neonatal care … Read more