Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer’s disease and epilepsy and may be a linking factor between the two diseases. The work, supported by FAPESP, confirms clinical evidence that people with epilepsy … Read more
While Alzheimer’s disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (Duncan NRI) and collaborating institutions provide a … Read more
A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer’s disease is underway at UTHealth Houston. In Alzheimer’s disease, deposits of beta-amyloid and tau lead to the buildup of plaques and tangles in the brain, which cause dementia. An estimated 6.9 million Americans age 65 and older are living with Alzheimer’s disease … Read more
A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer’s disease. Using human induced pluripotent stem cells (iPSCs), the international team has been able to show that a specific form of the tau protein, known as the 1N4R isoform, is responsible for … Read more