Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer’s disease (AD), but its role in the brain was unknown until now. In a paper published in Nature, researchers from Mass General Brigham used preclinical models to uncover Tim-3’s role in microglia, the brain’s resident immune cells, and have … Read more
Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors – a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made this concept a reality, crafting what they have named the “EchoBack CAR T-cell,” which could soon be a game changer in the field … Read more
Archyde Cancer’s Elusive shield: How Tumor Cells Outsmart the Immune system Table of Contents 1. Cancer’s Elusive shield: How Tumor Cells Outsmart the Immune system 2. Mitochondrial Transfer: A New Immune Evasion Tactic 3. The Downstream effects of mitochondrial Transfer 4. Targeting mitochondrial Transfer: A Novel Approach to Cancer Therapy 5. Could This Be a … Read more
Modifying the physical characteristics of microscopic biomaterials to interact seamlessly with the body’s tissues could unlock safer and more effective cancer treatments, according to Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC. In an online review slated for the Feb. 10 issue of the Journal of Controlled Release, a research team led by DaeYong … Read more
Researchers have developed a new method to grow T cells that have greater longevity and can more efficiently destroy cancer cells in mouse models of melanoma compared to those grown in traditional growth media Study: Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy. Image Credit: ART-ur/Shutterstock.com … Read more