A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilise the cancer genome. Unstable genomes are a fertile playground for cancer evolution, giving malignant cells more opportunities to grow, adapt and evade treatment. The researchers analyzed genome sequences from tumors with unusually high activity of LINE-1 … Read more
A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled “Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?” In this editorial, Iman M. Al-Naggar of the University of Connecticut School of Medicine, UConn Health, and the University of Connecticut Center on Aging, with George A. Kuchel of the University of Connecticut Center on Aging, examines the … Read more
A clinical trial for patients with high-grade neuroendocrine tumors is now open for enrollment at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. High-grade neuroendocrine cancer is a complex and aggressive condition that has seen few medical advances, in part because its rarity has subdued research investment. Patients have few options beyond … Read more