Cell Cycle

Polyploidy-induced senescence may influence aging and cancer risk

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A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled “Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?” In this editorial, Iman M. Al-Naggar of the University of Connecticut School of Medicine, UConn Health, and the University of Connecticut Center on Aging, with George A. Kuchel of the University of Connecticut Center on Aging, examines the … Read more

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

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Vitamin D’s anti-cancer powers go beyond bones, new findings reveal how it suppresses inflammation, boosts immune surveillance, and disrupts tumor development to guard against colorectal cancer. Study: Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications. Image Credit: crystal light / Shutterstock.com A recent study in the journal Nutrients reviews the role of vitamin … Read more

Study reveals ferulic acid’s potential in preventing colon cancer

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Colon cancer continues to be one of the leading causes of cancer-related deaths worldwide, with poor dietary habits identified as a major risk factor. Ferulic acid, a phenolic compound abundant in many plant foods, has previously demonstrated potential anti-cancer properties by inhibiting cell proliferation and promoting apoptosis. Despite its promising effects, the impact of ferulic … Read more

Gut microbes revealed as hidden drivers of aging and cellular decline

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New research reveals the gut microbiota’s surprising role in aging and highlights promising therapies to counteract its effects on cellular health. Study: Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence. Image Credit: Tatiana Shepeleva / Shutterstock A recent study published in the journal Nature Aging investigated the role of gut microbiota-derived phenylacetylglutamine (PAGln) in driving cellular senescence and … Read more