AI-based technology accelerates discovery of new tuberculosis drug candidates

Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and into the lungs, the pathogen that causes “TB” can lead to chronic cough, chest pains, fatigue, fever and weight loss. While infections are more extensive in other parts of the world, a serious tuberculosis … Read more

BP Readings in Noisy Market as Good as Quiet Office?

TOPLINE: Blood pressure (BP) measurements taken in a public space — with and without ambient noise — were minimally different from readings obtained in a private, quiet office. Mean systolic BP varied by less than 1 mm Hg between settings. Although guidelines advise measuring BP in a quiet place, public venues may be valid options … Read more

Ritlecitinib Shows Long-Term Benefits for Alopecia Areata

Archyde > Long-Term Efficacy and Safety of Ritlecitinib in Alopecia Areata Table of Contents 1. Long-Term Efficacy and Safety of Ritlecitinib in Alopecia Areata 2. Promising Results: Hair Regrowth Sustains Over Time 3. Safety Profile: Favorable Despite Side Effects 4. What Are the Key Differences Between the ALLEGRO-LT Study and Previous Ritlecitinib Trials for AA? … Read more

Ritlecitinib Shows Long-Term Benefits in Alopecia Areata

TOPLINE: Ritlecitinib demonstrates long-term improvements in regrowth of scalp hair, eyebrows, and eyelashes at 24 months in adults and adolescents with alopecia areata (AA) and ≥ 25% scalp hair loss. METHODOLOGY: Researchers evaluated outcomes in 449 de novo adult and adolescent patients (mean age, 32.9 years) with AA and ≥ 25% scalp hair loss, enrolled … Read more

Heavy Cannabis Use and Brain Activity in Young Adults

The Evolving Landscape of Cannabis and Cognition: What’s Next? Table of Contents The Evolving Landscape of Cannabis and Cognition: What’s Next? Unveiling the Brain’s Response to Cannabis Did You Know? Short-Term Effects and Long-Term Implications Pro Tip: Navigating the Complexities of Cannabis Use the Future of Cannabis Research FAQ Recent research has ignited a crucial … Read more

Heavy Cannabis Use May Alter Brain Activity

TOPLINE: Heavy lifetime cannabis use is linked to reduced brain activation during working memory tasks in young adults, while recent use is also associated with reduced activation during cognitive tasks, new research shows. METHODOLOGY: Researchers analyzed data collected between 2012 and 2015 from the Human Connectome Project. The cross-sectional study included more than 1000 young … Read more

CT-Based AI Offers Enhanced Sensitivity and Reduced Segmentation Time for Lung Tumors

Can deep learning provide viable automation of lung tumor detection and segmentation based on computed tomography (CT) scans? For a new retrospective study, recently published in Radiology, researchers assessed the capability of a deep learning model to detect and segment lung tumors in 150 chest CT cases. The overall cohort was comprised of 41 CT … Read more

Does Time-Restricted Eating Cut Extra Belly Fat?

TOPLINE: Time-restricted eating (TRE) doesn’t significantly reduce visceral adipose tissue (VAT) but leads to significant reductions in body weight compared with usual care in adults with overweight or obesity. METHODOLOGY: Although previous studies suggest that TRE may lead to modest weight loss and improvements in cardiometabolic health, the optimal timing of the eating window in … Read more

Feedback System Speeds Up Stroke Treatment

TOPLINE: Performance feedback reduces the time to endovascular thrombectomy (EVT) in patients with ischemic stroke, according to a Dutch study. METHODOLOGY: The researchers conducted a stepped-wedge cluster randomized PERFEQTOS trial in the Netherlands, which included 4747 consecutive adult patients with ischemic stroke who underwent EVT between January 2020 and June 2022. Hospitals started with usual … Read more

AI deciphers intracellular signals from extracellular recordings in heart cells

A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need to physically penetrate the cells. The method, published on Jan. 14 in Nature Communications, relies on recording electrical signals from … Read more