Seven cocaine smugglers jailed for between 10.5 and 12 years as a ‘significant deterrent’ – The Journal

Seven cocaine smugglers jailed for between 10.5 and 12 years as a ‘significant deterrent’  The Journal Seven jailed over conspiracy to import cocaine worth €42m  RTE.ie Smugglers who brought €42m worth of cocaine into State jailed  The Irish Times ‘Significant deterrent’ – men jailed over conspiracy to import cocaine worth millions  Limerick Leader Source link

Scientists turn red blood cells into long-lasting drug and imaging carriers in mice

A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting carriers for imaging agents and therapies, opening a new route for safer drug delivery and vascular imaging. Study: In vivo metabolic tagging and targeting of circulating red blood cells. Image Credit: The1969 Studio / Shutterstock In a … Read more

Study finds GLP-1 medicines cut fat while preserving muscle function

A new study in mice and humans suggests GLP-1 medicines drive weight loss primarily by reducing fat, while preserving muscle function and easing fears about harmful muscle wasting. Key takeaways Fat, not skeletal muscle, accounted for most of the weight loss. According to the study, GLP-1 medicines reduced body fat in obese mice much more … Read more

Dublin flushed more ketamine into wastewater last year than it did in 2024

We need your help now Support from readers like you keeps The Journal open. You are visiting us because we have something you value. Independent, unbiased news that tells the truth. Advertising revenue goes some way to support our mission, but this year it has not been enough. If you’ve seen value in our reporting, … Read more

Lysosomal storage of drugs may influence cancer treatment outcomes

One of oncology’s biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, from a multi-disciplinary team led by Dr Louise Fets at the LMS, has mapped the distribution of a type of targeted treatments, known as PARP inhibitors, using advanced imaging techniques and patient ovarian tumour samples. The research reveals that build up of these drugs in lysosomes – small compartments inside cells that normally act as “recycling centres” – can trap and … Read more

Man caught with cocaine in Letterkenny hotel room is fined

A young Letterkenny man has been fined €400 after being caught with cocaine in a Letterkenny hotel. Felix Connors appeared before Letterkenny District Court charged with two drugs offences. The 19-year-old, with an address at Canal Road in Letterkenny, was represented by solicitor Michael Shiel. Garda Sergeant Jim Collins outlined the details of both cases … Read more

Patients who stop GLP-1 drugs often restart or try alternatives

A large real-world study shows that patients who stop popular GLP-1–based weight-loss drugs often return to treatment or try alternative therapies, helping explain why average weight regain after discontinuation may be smaller than expected. Study: Obesity Treatments and Weight Changes in Clinical Practice After Discontinuation of Semaglutide or Tirzepatide. Image credit: KaterynaBorodina/Shutterstock.com Obesity treatment has … Read more

BOC seizes P262M illegal drugs, smuggled cigarettes

BUREAU of Customs (BOC) operatives intercepted over the weekend P27 million worth of illegal drugs inside a hotdog roller machine in an interdiction operation conducted at a warehouse in Pasay City. Customs Commissioner Ariel Nepomuceno on Sunday said the operation, conducted in coordination with the NAIA Inter-Agency Drug Interdiction Task Group, resulted in the discovery … Read more

P237.8M illegal drugs, P25.8M ‘hot’ items seized

OVER P237.8 million worth of illegal drugs and P25.8 million in smuggled goods were seized in a two-day operation from March 11-12, resulting in the arrest of most-wanted persons from Davao del Norte, Baguio City, South Cotabato, Misamis Oriental, Surigao del Sur, and regional-level suspects in Calabarzon and Laguna, the Philippine National Police (PNP) said. … Read more

Two arrested after €5.25m of cocaine seized in Monaghan during operation involving Belgian Police – The Journal

Two arrested after €5.25m of cocaine seized in Monaghan during operation involving Belgian Police  The Journal Two arrested after cocaine worth €5m seized in Monaghan  RTE.ie Cocaine worth more than €5m recovered in Garda raid  The Irish Times Cocaine worth €5.25m seized and two arrested  BBC Man and woman arrested as gardaí seize cocaine worth €5.25m in Monaghan  The Irish … Read more