Long-term proton pump inhibitor use not linked to stomach cancer

The long term use of proton pump inhibitors (PPIs), a class of drugs widely used to treat acid reflux and ulcers, may not be linked to any increased risk of developing gastric (stomach) cancer, finds a study of Nordic health data published by The BMJ today. This finding should offer relief for patients needing long term proton … Read more

Newly discovered survival pathway explains stubborn EGFR-driven lung cancers

Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified why certain lung cancer cells become highly resistant to treatment after developing mutations in a key gene called EGFR (epidermal growth factor receptor). In a study published in Science Advances, the researchers revealed a previously unknown survival mechanism and demonstrated that disrupting … Read more

Study finds growing long-term antipsychotic prescribing in elderly dementia patients

When agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing to increases in antipsychotic treatment rates among older people. Indeed, a research letter by Rutgers and Columbia University researchers in … Read more

Study reveals how ketogenic diet protects against epilepsy seizures

University of Virginia School of Medicine researchers have revealed how the popular, low-carb ketogenic diet protects against epilepsy seizures and possibly neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Keto, as the diet is commonly known, has been used to reduce seizures in patients with medication-resistant epilepsy since the 1920s. Doctors, however, have been uncertain exactly … Read more

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and immune checkpoint inhibitor drugs, but it’s not always clear which therapy is inducing what type of response. To help drive further study, investigators from the Johns Hopkins Kimmel Cancer Center have made public a free, web-based atlas … Read more

Gut microbiota analysis offers insights into how ultra processed foods affect health

To gain more knowledge about how ultra-processed food affects us, we need new research methods, claim researchers. Now they are looking to better understand our intestinal flora.   Wilhelm Glomm is one of the researchers at the Department of Biotechnology and Nanomedicine at SINTEF. He is interested in how the content of ultra-processed food can … Read more

New review examines the growing global use of melatonin among pediatric populations

Sleep problems are increasingly common among children and adolescents, affecting emotional regulation, cognitive development, and healthy conditions. As families are seeking quick and accessible solutions, melatonin supplements have gained widespread popularity due to their availability, child-friendly formulations, and perception as a safe, natural alternative to prescription drugs. Yet melatonin is a kind of hormone that … Read more

Incretin-based diabetes drugs show potential protective effects against dementia

A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes, both incretin-based, are associated with a reduced risk of dementia. Drawing on clinical data from more than 450,000 patients, the research adds to growing evidence that incretin-based therapies have protective benefits for the brain. The study examined GLP-1 … Read more

Death penalty looms for American, Kazakhs over Bali drug charges, say Indonesian authorities

DENPASAR, June 5 — An American man and two Kazakh nationals face the death penalty for alleged drug crimes on the popular Indonesian resort island of Bali, authorities said Thursday, the latest cases in a nation with some of the world’s toughest narcotics laws. Indonesia hands out severe punishments for drug smuggling and has previously … Read more