Engineered liver tissue model mimics early metabolic liver disease

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead to the development of more severe liver disease that causes inflammation and fibrosis. In hopes of discovering new treatments for these liver diseases, MIT engineers … Read more

Three men accused of operating ‘cocaine bulking factory’ from Dublin bedroom granted bail

We need your help now Support from readers like you keeps The Journal open. You are visiting us because we have something you value. Independent, unbiased news that tells the truth. Advertising revenue goes some way to support our mission, but this year it has not been enough. If you’ve seen value in our reporting, … Read more

Gardaí have seized €3.4m worth of Benzodiazepine tablets in Dublin

We need your help now Support from readers like you keeps The Journal open. You are visiting us because we have something you value. Independent, unbiased news that tells the truth. Advertising revenue goes some way to support our mission, but this year it has not been enough. If you’ve seen value in our reporting, … Read more

Chemical inhibitor helps viruses overcome bacterial immune defenses

Antimicrobial resistance – when bacteria and fungi defend themselves against the drugs design to kill them – is an urgent threat to global public health, according to the Centers for Disease Control and Prevention. To combat this threat, the Gerdt Lab at Indiana University Bloomington studies how to weaken bacteria’s defenses against viruses. “Bacteria get sick, … Read more

New mode of communication inside cells helps bacterial pathogens to evade drugs

Biologists have uncovered a new mode of communication inside cells that helps bacterial pathogens learn how to evade drugs. Their findings, published in the journal Nature Communications, describe how these mechanisms drive antimicrobial resistance in Listeria monocytogenes, the foodborne bacteria that causes listeriosis.  The work is a collaboration between researchers at the University at Albany and … Read more

Combination therapy improves cognition in Alzheimer’s models

In recent years, research into cannabis and its main psychoactive ingredient, Δ⁹-tetrahydrocannabinol (THC), has unearthed medical benefits including anti-inflammatory and neuroprotective properties. However, THC is also known to negatively affect learning and memory, limiting its potential clinical usefulness, particularly in disorders of the brain. Now, a new study led by Chu Chen, PhD, professor in … Read more

Urate-lowering gout treatment can reduce the risk of heart attack and stroke

A groundbreaking new study, led by experts at the University of Nottingham, has found that medicines used to treat gout can also reduce the risk of heart attack and stroke in people with gout. The new research, which is published in JAMA Internal Medicine, shows that treating gout to target blood urate levels also prevents … Read more

Improving survival in people with severe psychiatric disorders

An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap faced by people with serious mental illnesses by tackling cardiovascular risk and metabolic disease head-on. Editorial: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have potential to transform health outcomes for persons with bipolar disorder, schizophrenia, major depressive disorder … Read more

Estrogen-Free Relief: A New Bet for [Condition/Symptom]

A recent American study reveals that an experimental drug, elinzanetant, could revolutionize the treatment of menopausal… The post Estrogen-Free Relief: A New Bet for [Condition/Symptom] appeared first on Archynetys. Source link