New mouse model sheds light on smell loss and neural regeneration

A new study suggests that stem cells thought to be dormant may offer clues to why our sense of smell declines or is lost. Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered … Read more

3 Things a Scientist Does to Reduce Inflammation Via the Vagus Nerve

Psychotherapists, yoga teachers, and self-help types such as Mel Robbins have been talking about stimulating the vagus nerve as a way to “reset” the nervous system and calm anxiety for years. But growing evidence suggests it could do far more for our health: By helping keep inflammation at bay, the vagus nerve could be the … Read more

Longer breastfeeding boosts brain growth and thinking skills in teens, study shows

New research reveals that extended breastfeeding benefits infants and helps adolescents build stronger brains and sharper thinking, highlighting the long-term value of following global breastfeeding recommendations. Study: Sustained breastfeeding associations with brain structure and cognition from late childhood to early adolescence. Image Credit: Kittyfly / Shutterstock Breastfeeding’s neurocognitive benefits on infants and children are generally supported, although … Read more

Ubrogepant relieves early migraine symptoms and may help prevent full-blown attacks

Treating migraine before the pain starts: New research shows ubrogepant eases premonitory symptoms, offering hope for millions seeking earlier and more effective relief. Study: Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial. Image Credit: GoodStudio / Shutterstock The most recent exploratory analysis from the phase 3 PRODROME … Read more

Injecting medicine into amniotic fluid shows promise for treating genetic disorders

Injecting medicine into the amniotic fluid staves off progression of spinal muscular atrophy in utero.  Evidence is mounting that clinicians can treat serious genetic disorders prenatally by injecting medicine into the amniotic fluid, thus preventing damage that begins in utero. A UC San Francisco-led study found that delivering medicine for spinal muscular atrophy (SMA) via … Read more

Study shows brain estrogen directly regulates appetite in mice

By pinpointing how neuroestrogen directly boosts appetite-suppressing receptors in the brain, scientists are laying the groundwork for precision therapies that could tackle obesity from within the central nervous system. Study: Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake. Image Credit: r.classen / Shutterstock A study led by researchers at the Fujita … Read more

Internal appetite signals vary with socioeconomic background

Published in the journal Food Quality and Preference, the research highlights how physiological signals, particularly those transmitted via the vagus nerve, interact with socio-economic factors to shape dietary behavior.  The study involved 96 students from diverse socio-economic backgrounds who participated in a chocolate tasting session.  In a controlled laboratory setting, each participant was presented with a … Read more

Can gut microbes help prevent Alzheimer’s?

From the Mediterranean diet to microbial metabolites, scientists reveal how maintaining gut health could be a powerful strategy to delay or prevent Alzheimer’s disease. Review: Microbial diversity and fitness in the gut–brain axis: influences on developmental risk for Alzheimer’s disease. Image Credit: Volodimir Zozulinskyi / Shutterstock In a recent review in the journal Gut Microbes, researchers at … Read more

New method traces development of nervous system and inner ear cells

Researchers at Karolinska Institutet have developed a method that shows how the nervous system and sensory organs are formed in an embryo. By labeling stem cells with a genetic ‘barcode’, they have been able to follow the cells’ developmental journey and discover how the inner ear is formed in mice. The discovery, published in Science, … Read more