TOPLINE: Four clinical organizations jointly released a clinical advisory with evidence-based nutrition and lifestyle interventions to enhance glucagon-like peptide 1 (GLP-1) treatment outcomes for obesity. METHODOLOGY: An expert group comprised of multiple clinical and research disciplines assessed the literature to identify pragmatic priorities for nutrition and other lifestyle interventions relevant to GLP-1 treatment for obesity. … Read more
TOPLINE: A recent study found that antiretroviral therapy adherence below 90% was associated with significantly lower odds of viral suppression among women living with HIV. METHODOLOGY: Researchers analyzed data from community-based prospective cohort study including women living with HIV across British Columbia, Ontario, and Quebec between 2013 and 2018. Overall, 1187 participants (median age, 42 … Read more
TOPLINE: An emergency department (ED)–based alert led to a higher rate of A1c testing among patients with diabetes overdue for routine monitoring but did not significantly improve long-term glycemic control. METHODOLOGY: In this retrospective study, the researchers analyzed 348,490 ED visits by patients with diabetes from January 2017 to September 2023. In November 2017, an … Read more
The Evolving Landscape of Colorectal Cancer Screening: Balancing Convenience and Accuracy Table of Contents The Evolving Landscape of Colorectal Cancer Screening: Balancing Convenience and Accuracy The Challenge of Screening Adherence The Appeal of Blood-Based Screening A Closer Look at Performance and Limitations the Importance of Follow-Up and Future Directions The Ongoing Debate: Optimizing Colorectal Cancer … Read more
TOPLINE: In a modeling analysis, initiating direct acting or nonvitamin K oral anticoagulants (DOAC/NOAC) in patients with device-detected subclinical atrial fibrillation (AF) provided a net gain of approximately 1 additional quality-adjusted week of life per patient over 10 years, equating to a 65.8% chance of treatment offering more benefits than withholding it. METHODOLOGY: Previous randomized … Read more
What’s Stalling PrEP’s Success in Europe’s HIV Fight Medscape Source link
Rethinking Antibiotic Duration for Childhood UTIs: A New Approach to Treatment Table of Contents Rethinking Antibiotic Duration for Childhood UTIs: A New Approach to Treatment shorter Antibiotic Courses for kids’ UTIs: New Research & Guidelines The Evolving Landscape of Pediatric UTI Treatment What the Latest Research Shows understanding Uncomplicated UTIs in Children Diagnosing a UTI … Read more
TOPLINE: In children with febrile urinary tract infections (UTIs), individualised antibiotic treatment stopping at 3 days after the achievement of adequate clinical improvement compared with the standard 10-day treatment regimen increased the risk for recurrent infections but reduced antibiotic use and the number of days of adverse events. METHODOLOGY: Researchers conducted a pragmatic trial (INDI-UTI) … Read more
TOPLINE: Among children with a history of severe bronchiolitis during infancy, low serum 25-hydroxyvitamin D (25(OH)D) levels ( METHODOLOGY: Researchers conducted a prospective study to examine the association between serum 25(OH)D levels at the age of 3 years and the risk for the onset of eosinophilic asthma by the age of 6 years among children … Read more
BERLIN — Adherence to a healthy plant-based diet is associated with a reduced risk of developing inflammatory bowel disease (IBD), whereas an unhealthy plant-based diet is linked to an increased disease risk and worse outcomes, according to the results of a large cohort study. The study, which included both Crohn’s disease (CD) and ulcerative colitis … Read more