Patients with advanced solid tumors experienced significantly improved survival outcomes when receiving a tailored therapy based on the detection of the same genomic alteration in both tissue and liquid biopsies compared with both standard-of-care treatment and tailored therapy that was based on either biopsy on its own, according to results from the phase II, multicenter ROME … Read more
Stanford Medicine researchers have developed a blood test capable of detecting cancers, the ways cancer resists treatments and tissue injury caused by non-cancerous conditions. The new test analyzes RNA molecules in the bloodstream. This type of RNA is called cell-free RNA because the tiny molecules no longer inhabit a cell. There are always fragments of … Read more
Archyde Expert Groups Advocate for Refined Approach to Diagnosing Indolent prostate Cancer May 8, 2025 Two leading international pathology societies are urging a shift in how indolent prostate cancers are detected and diagnosed, aiming to reduce overtreatment and improve patient outcomes. Teh Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP) recently … Read more
TOPLINE: A dry suction technique was noninferior to a wet suction technique for endoscopic ultrasound–guided fine-needle biopsy (EUS-FNB) in patients with solid pancreatic lesions, with comparable diagnostic accuracies. A single needle pass achieved more than 90% accuracy in both the techniques. METHODOLOGY: This randomized noninferiority trial conducted across four hospitals in China (2022-2024) assessed the … Read more
In a new case study, researchers from North Carolina State University found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis. The findings further support the idea that these pathogens can be a cofactor in complex neurological illnesses. Bartonella are a group of vector-borne bacteria transmitted … Read more
New research shows that Vitamin E therapy significantly enhances liver function and reduces inflammation in MASH patients, providing a safer and effective treatment option in the fight against metabolic liver disease. Study:Â Vitamin E (300Â mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study In a recent study published in the journal Cell Reports … Read more
Despite similar availability of diagnostic technologies to women of different racial and ethnic groups, significant disparities were seen in who actually received same-day diagnostic services and biopsies after abnormal mammogram findings, new research shows. Even when breast-care facilities had the necessary technology and capabilities, minority groups were less likely than white women to receive diagnostic imaging … Read more
For years, breast cancer treatment has been guided by genetic alterations found in tumor tissue, typically through invasive biopsies. However, the dynamic nature of cancer and limitations in tissue sampling have presented significant obstacles for clinicians. circulating tumor DNA (ctDNA), which is released into the bloodstream by tumor cells, offers a promising non-invasive alternative. It … Read more
A new blood test has an 80% accuracy in predicting preterm preeclampsia, according to a study published today, Feb. 12, in the journal Nature Medicine. The condition, which results in over 70,000 maternal deaths and 500,000 fetal deaths each year worldwide, has long been hard to predict. This makes proactive treatment challenging, according to one of the study’s lead … Read more
TOPLINE: Patients with clinically node-negative breast cancer after neoadjuvant chemotherapy demonstrated low axillary and locoregional recurrence rates after sentinel lymph node biopsy (SLNB) or targeted axillary dissection. METHODOLOGY: More conservative treatment options for women with node-positive breast cancer include SLNB and targeted axillary dissection. However, data comparing patient outcomes after targeted axillary dissection and SLNB … Read more