AI and human scientists collaborate to discover new cancer drug combinations

An ‘AI scientist’, working in collaboration with human scientists, has found that combinations of cheap and safe drugs – used to treat conditions such as high cholesterol and alcohol dependence – could also be effective at treating cancer, a promising new approach to drug discovery. The research team, led by the University of Cambridge, used … Read more

Necrosis: Key to Longevity & Space Health?

Archyde: Latest World News, Economy, Entertainment, Health, Technology & Sports Updates Necrosis: Unlocking Secrets of Cell Death to Combat Aging and Disease London, United kingdom – Groundbreaking research illuminates how necrosis, a form of cell death, could revolutionize our approach to… You can read the full story here: Necrosis: Key to Longevity & Space Health?. … Read more

Autism: Impaired Synaptic Pruning?

Archyde Impaired Synaptic Pruning in Autism: Immune Cell Dysfunction Identified Table of Contents 1. Impaired Synaptic Pruning in Autism: Immune Cell Dysfunction Identified 2. The Role of synaptic Pruning in Brain Growth 3. Macrophages and Synaptic Clearance: A New Clue 4. CD209 Gene: A Potential Mediator 5. Implications for Future Therapies 6. Source: 7. Frequently … Read more

Study links impaired synaptic pruning to autism

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests. A growing body of research suggests that neurobiological changes, particularly abnormalities in dendritic spines, tiny protrusions on nerve cells where synapses form, may be a hallmark of ASD. … Read more

New Coronavirus Drug Candidates: Promising Research

A team at UC San Francisco and Gladstone Institutes has developed new drug candidates that show great promise against the virus that causes COVID-19 and potentially other coronaviruses… The post New Coronavirus Drug Candidates: Promising Research appeared first on NewsyList. Source link

Newly Discovered Immune Cell Type Regulates Food Allergies

The gastrointestinal tract is continuously exposed to foreign antigens in food and commensal microbes that have the potential to induce adaptive immune responses for food allergies.  In a new study published by Nature titled, “Prdm16-dependent antigen-presenting cells induce tolerance to gut antigens,” researchers from New York University (NYU) Langone Health have revealed that a special … Read more

Huntington’s Disease Progression May Be Slowed by Regenerative Strategy

Research in a mouse model of Huntington’s disease has shown that the adult brain can generate new neurons that integrate into key motor circuits. Building on previous work, the new findings, by a team at the Center for Translational Neuromedicine, University of Rochester Medical Center (URMC), demonstrated that stimulating natural brain processes may help repair … Read more

Gut Bacteria Can Impact the Effectiveness of GPCR-Targeting Drugs

Credit: igoriss / iStock / Getty Images Plus A new study from researchers at the University of Pittsburgh and Yale University shows how common bacteria found in the human gut can influence how medications that target G protein-coupled receptors (GPCRs) are metabolized, rendering them less effective. The study, published in Nature Chemistry, could have implications … Read more

OICR funds five innovative cancer drug discovery projects

The Ontario Institute for Cancer Research (OICR) has announced its support for five Ontario research teams working to develop the next generation of medicines that kill tumours more effectively, cause fewer side effects and reduce the risk that cancer will come back. The projects will be funded as part of OICR’s Cancer Therapeutics Innovation Pipeline … Read more

New protein target could aid in muscle regeneration for degenerative conditions

For millions of people, losing muscle isn’t just about weakness; it’s about losing independence. Whether caused by Duchenne muscular dystrophy, aging or other degenerative conditions, muscle loss can make everyday activities – like walking, climbing stairs or even standing up – a daily struggle. But a recent discovery from researchers at the University of Houston … Read more