New breath test could quickly diagnose bacterial infections

Infectious diseases are a major cause of death worldwide, and diagnosing bacterial infections remains a challenge in medicine. And doing so reliably is more important than ever, given the increasing frequency of antibiotic resistance. Now, research published in ACS Central Science could help healthcare professionals non-invasively diagnose bacterial infections, using breath-based tests. Initial experiments demonstrated the approach in animals with pneumonia and infections in the bloodstream, muscles and bones.  In designing … Read more

Lysosomal storage of drugs may influence cancer treatment outcomes

One of oncology’s biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, from a multi-disciplinary team led by Dr Louise Fets at the LMS, has mapped the distribution of a type of targeted treatments, known as PARP inhibitors, using advanced imaging techniques and patient ovarian tumour samples. The research reveals that build up of these drugs in lysosomes – small compartments inside cells that normally act as “recycling centres” – can trap and … Read more

Researchers use multiview deep learning to enhance echocardiogram analysis

Heart disease is the leading cause of adult death worldwide, making cardiovascular disease diagnosis and management a global health priority. An echocardiogram, or cardiac ultrasound, is one of the most commonly used imaging tools employed by physicians to diagnose a variety of heart diseases and conditions.  Most standard echocardiograms provide two-dimensional visual images (2D) of the three-dimensional (3D) cardiac anatomy. These echocardiograms often capture hundreds of 2D slices or views of a … Read more

Psychiatrists’ use of biomarkers could open a new window into mental health diagnoses

Amanda Miller was 30 and pregnant with her second child in Hershey, Pennsylvania, when she developed depression. After she gave birth, her depression worsened. It was joined by a slew of unexplained health problems. Miller, a neuroscientist, said she saw several psychiatrists and got prescriptions for drug after drug. Over two years, she tried four … Read more

Stress hormones disrupt the internal GPS system of the brain

Persons under stress may have a harder time spatially orienting themselves. Researchers in Bochum have discovered why. The stress hormone cortisol disrupts the brain’s navigational system. It impairs the function of the grid cells that play a crucial role in orientation. This has been verified by researchers from Ruhr University Bochum, Germany, in an imaging … Read more

New AI system reduces pathologist workload while maintaining diagnostic accuracy

Artificial intelligence could make cancer diagnosis safer and fairer by learning when to defer to human pathologists without overloading them, according to researchers from the University of Surrey and Monash University. The approach tackles two critical problems that have limited the use of AI-assisted decision-making in cancer pathology, radiology and other fields where human expertise … Read more

Using machine learning to identify individuals at risk for intimate partner violence

Researchers at Mass General Brigham have developed a series of artificial intelligence (AI) tools that uses machine learning to identify individuals who may be at risk for intimate partner violence (IPV) using information from their electronic medical records (EMRs). In a study published in npj Women’s Health, the researchers report the tools could detect IPV … Read more

Iconeus expands U.S. presence to support growing adoption of fUS in preclinical brain imaging

Iconeus, a French neuroimaging company developing functional ultrasound (fUS) solutions for real-time brain activity imaging, today announced the creation of its U.S. entity, Iconeus Inc. – a key milestone in supporting the adoption of functional ultrasound in preclinical neuroscience research. The new U.S. presence will enable closer collaboration with American academic laboratories, research institutes, pharmaceutical … Read more

Study reveals racial differences in early Alzheimer’s brain changes

A team of researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has identified important differences in how early Alzheimer’s disease-related brain changes appear across racial and ethnic groups, underscoring the need for more inclusive approaches to studying and diagnosing the disease. … Read more

International urology conference showcases advancements in prostate cancer diagnostics

Nearly 300 abstracts on prostate cancer research from around the world will be presented at the European Association of Urology Congress (EAU26), taking place in London from 13–16 March 2026. Highlights of some of the key advances in the prostate cancer screening field are detailed below. Tobias Nordström is a clinical urologist and Associate Professor … Read more