High HDL cholesterol may increase glaucoma risk in older adults

‘Good’ (HDL) cholesterol, usually considered to be beneficial for health, may be linked to a heightened risk of the serious eye condition, glaucoma-at least among the over 55s- suggest the results of a large observational study, published online in the British Journal of Ophthalmology. Paradoxically, ‘bad’ (LDL) cholesterol, usually regarded as harmful to health, may be … Read more

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) – Institut Català d’Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves. The findings have been published in the journal Clinical Cancer Research. A rare aggressive tumor arising in the nerves It … Read more

New drug may help restoring vision for people with nerve damage: Study

Colorado [US], January 25 (ANI): Researchers at the University of Colorado Anschutz Medical Campus found a promising therapeutic candidate that could aid in the restoration of vision in those suffering from multiple sclerosis (MS) and other neurodegenerative diseases. The medicine, LL-341070, improves the brain’s ability to repair damaged myelin–the protective sheath that surrounds nerve fibers. … Read more

APOBEC proteins linked to DNA repeat expansion in Huntington’s disease

People genetically susceptible to Huntington’s disease often see their movement, mood, and cognition decline slowly over time.  The cause is related to expansion of repeating DNA units, in which specific strings of genetic code-in this case, a series of cytosine-adenine-guanine nucleotides, or CAG, on one strand of the DNA and cytosine-thymine-guanine, or CTG, on the complementary … Read more

Study reveals biotin’s potential to mitigate manganese-induced brain damage

While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues. Maintaining a balanced diet typically provides sufficient manganese for most individuals; however, high levels of exposure can be toxic, particularly to the central nervous system. Chronic manganese exposure may result in a condition known as … Read more

Innovative AI approach enhances imaging in thick biological samples

Depth degradation is a problem biologists know all too well: The deeper you look into a sample, the fuzzier the image becomes. A worm embryo or a piece of tissue may only be tens of microns thick, but the bending of light causes microscopy images to lose their sharpness as the instruments peer beyond the … Read more

Nogo-A inhibition demonstrates potential for spinal cord injury recovery

The latest study results have been published online in the renowned “The Lancet Neurology” journal. A multi-centre clinical trial (NISCI trial: Nogo-A Inhibition in acute Spinal Cord Injury Study) investigated the antibody NG 101 (anti-Nogo-A), which blocks and thus neutralizes the body’s own Nogo-A protein. Several international studies in animal models have shown that this … Read more

Chronic gut infection may play role in Alzheimer’s disease progression

Arizona State University and Banner Alzheimer’s Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer’s disease in a subset of people. It is believed most humans are exposed to this virus -; called cytomegalovirus or HCMV -; during the … Read more