A new study has found that a prebiotic fiber supplement reduced pain, improved grip strength, and lowered pain sensitivity in people with knee osteoarthritis (OA) – with far fewer dropouts than a digital physiotherapy programme. The INSPIRE clinical trial, led by experts at the University of Nottingham, showed that taking a daily supplement of inulin- a … Read more
Post-traumatic osteoarthritis often affects younger, active individuals and progresses quickly following ligament or cartilage injury. Chondrocytes, the sole cell type in articular cartilage, survive in a low-oxygen environment by relying heavily on glycolysis, producing large amounts of lactate. While lactate has traditionally been associated with tissue stress and inflammation, emerging evidence suggests it also functions … Read more
When teaching assistant Kavita Biswas first asked for a wheelchair at the airport, she was struggling to walk even short distances. It was a world away from her active life practising yoga and dance alongside her full-time job in a Hong Kong school. Suddenly, in her mid-forties, she found herself relying on a cane and, … Read more
The effectiveness of exercise therapy to ease the symptoms of osteoarthritis is likely minimal, short lived, and probably no better than no treatment at all, suggests an overarching (umbrella) systematic review and pooled data analysis of the available evidence, published in the open access journal RMD Open. The findings question the universal promotion of exercise as … Read more
Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease progression before cartilage loss. Using spatial mass spectrometry imaging and synovial fluid proteomics, researchers identified bone-derived protein signatures beneath intact cartilage that were also detectable in joint … Read more
A sweeping genetic analysis reveals when obesity is the common thread linking chronic diseases, and when other biology is to blame. Study: Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions. Image credit: MaskaRad/Shutterstock.com A recent study in Communications Medicine completed a genetic analysis to determine whether body mass index (BMI) affects … Read more
Scientists have identified a promising new method to regenerate cartilage by targeting a single enzyme linked to aging, a finding that could eventually change how osteoarthritis and joint damage are treated. The study, published in Science, showed that inhibiting an enzyme called 15-PGDH allowed damaged cartilage in mice to regenerate without the need for stem … Read more
According to new research from the University of Delaware, nearly 40% of American adults ages 18 to 64 with arthritis – almost 10 million people – say the medical condition is limiting their ability to work. Co-author Daniel White, associate professor of physical therapy at UD, analyzed findings from the 2023 National Health Interview Survey, which was recently published in the … Read more
Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally. Projections suggest that this number will rise to 1 billion by 2050. Despite its profound impact on individuals and societies, no disease-modifying treatments are currently available. Now, an international team of researchers led by Helmholtz Munich has … Read more
Novel Joint Repair Method Shows Promise in Preventing Osteoarthritis Table of Contents Novel Joint Repair Method Shows Promise in Preventing Osteoarthritis Agrin-Derived Polypeptide: A Catalyst for Cartilage Regeneration… The post Osteochondral Defect Repair: Queen Mary Breakthrough appeared first on NewsyList. Source link