The effectiveness of exercise therapy to ease the symptoms of osteoarthritis is likely minimal, short lived, and probably no better than no treatment at all, suggests an overarching (umbrella) systematic review and pooled data analysis of the available evidence, published in the open access journal RMD Open. The findings question the universal promotion of exercise as … Read more
Chemotherapy remains one of the most powerful tools in the fight against cancer, yet it often comes with significant long-term side effects that can dramatically affect patients’ quality of life. Among the most debilitating is Chemotherapy-Induced Peripheral Neuropathy, which impacts both the central and peripheral nervous systems and affects up to 85% of cancer patients … Read more
Nearly all the world’s 10.6 million children experiencing serious health-related suffering (SHS) live in low- and middle-income countries with little to no access to palliative care specialized care for their illness, according to a comprehensive new report published in The Lancet Child & Adolescent Health. The study defines SHS as physical, psychological, social or spiritual … Read more
Osteoarthritis often goes undetected until cartilage damage is advanced, limiting treatment options. A new study shows that molecular changes in subchondral bone occur earlier and can signal disease progression before cartilage loss. Using spatial mass spectrometry imaging and synovial fluid proteomics, researchers identified bone-derived protein signatures beneath intact cartilage that were also detectable in joint … Read more
Neuropathic pain, caused by injury or disease of the somatosensory nervous system, is a major clinical… The post Electroacupuncture: Anxiety & Pain Relief – Neural Effects appeared first on Archynetys. Source link
Neuropathic pain, caused by injury or disease of the somatosensory nervous system, is a major clinical challenge and often evolves into a chronic condition. Importantly, up to 80% of patients with long-term pain also experience anxiety or depression. This creates a vicious cycle that not only worsens prognosis and quality of life but also poses … Read more
Griffith University researchers are on the cusp of a new vaccine to prevent chikungunya, a global health threat which attacks human joint tissue. Professor Bernd Rehm, from Griffith’s Institute for Biomedicine and Glycomics, said his team wanted to test whether they could engineer E.coli to assemble biopolymer particles which displayed chikungunya antigens and performed as … Read more
Opioid overdoses continue to take a devastating toll across the United States. According to the U.S. Centers for Disease Control and Prevention (CDC), in 2023, the nation recorded roughly 105,000 drug overdose deaths overall, with nearly 80,000 deaths involving opioids. Worldwide, opioids are also responsible for the majority of drug-related deaths. A University of California … Read more
Researchers from The University of Texas at Dallas and their international colleagues have determined the molecular signature of human sleeping - or silent - nociceptors: sensory neurons that are unresponsive to touch or pressure yet are key culprits in neuropathic pain. The findings suggest a potential pathway for finding drug targets to relieve chronic pain, … Read more
Researchers from the Centre for Addiction and Mental Health (CAMH) and the Institute of Neurophysiology at Uniklinik RWTH Aachen in Germany have deciphered the molecular signature of so-called sleeping nociceptors-a type of pain-sensing nerve cell that normally remains quiet and does not respond to touch or pressure, but can become overactive and drive chronic pain. … Read more