UCF researcher explores insulin signaling as new target for diabetic neuropathy

Neuropathy – chronic pain, numbness and tingling in the hands and feet – is a challenging fact of life for many patients with Type 1 diabetes. Thanks to a new National Institutes of Health grant, a University of Central Florida (UCF) College of Medicine scientist is investigating a new approach to treat neuropathy without relying on … Read more

Tiny organism offers insight into neurological side effects of chemotherapy

Chemotherapy remains one of the most powerful tools in the fight against cancer, yet it often comes with significant long-term side effects that can dramatically affect patients’ quality of life. Among the most debilitating is Chemotherapy-Induced Peripheral Neuropathy, which impacts both the central and peripheral nervous systems and affects up to 85% of cancer patients … Read more

Study identifies genetic fingerprint of neuropathic pain neurons

Researchers from The University of Texas at Dallas and their international colleagues have determined the molecular signature of human sleeping -­ or silent -­ nociceptors: sensory neurons that are unresponsive to touch or pressure yet are key culprits in neuropathic pain. The findings suggest a potential pathway for finding drug targets to relieve chronic pain, … Read more

Genetic discovery sheds light on infection-triggered neuropathy

Neuropathy, a disorder in which damage to nerves can impair sensation and movement, has many causes, including infection. Now, researchers from the UK have identified distinct genetic changes in a newly-discovered neuropathy and believe that their work will provide insights into the causal mechanism and why some previously healthy people develop neuropathies after infection whereas … Read more

Confocal Microscopy: Identifying Chemotherapy-Induced Neuropathy Biomarkers

Archyde: Latest World News, Economy, Entertainment, Health, Technology & Sports Updates Revolutionizing Cancer Care: early Detection of Chemotherapy-Induced Peripheral Neuropathy Chemotherapy, a cornerstone of cancer treatment, frequently enough comes with debilitating side effects. Among the most prevalent is chemotherapy-Induced Peripheral Neuropathy (CIPN), a nerve-damaging condition affecting countless patients. But what if early detection, before symptoms … Read more

Confocal microscopy may help identify biomarkers for chemotherapy-induced neuropathy

A University of Arizona Comprehensive Cancer Center researcher received a $2.4 million National Cancer Institute grant to develop a noninvasive, confocal microscope to examine nerve endings of cancer patients with chemotherapy-induced peripheral neuropathy in the hopes of identifying potential biomarkers for the disease. Peripheral neuropathy is a common side effect of certain chemotherapy drugs. Chemotherapy-induced peripheral neuropathy, or CIPN, … Read more

Study explores how Adapted Argentine tango dance therapy can help breast cancer survivors

Adapted Argentine tango dance therapy is helping some breast cancer survivors regain natural balance and sensation after experiencing neuropathy, a common side effect of chemotherapy treatment. Expansion of a new clinical study will look further at how this musical movement intervention can “rewire” the brain to improve function after chemotherapy-related nerve changes.  Lise Worthen-Chaudhari, PhD … Read more

Digital lifestyle program cuts diabetes risk by 46% in prediabetics, study of 130k+ adults reveals

Could a 45-minute weekly digital coach be the key to reversing diabetes? New study of 130k+ adults shows dramatic risk reduction and remission rates, without pills or extreme diets. Study: Lifestyle Modification in Prediabetes and Diabetes: A Large Population Analysis. Image Credit: RSplaneta / Shutterstock In a recent article published in the journal Nutrients, researchers in the … Read more

Popular Joint Supplement Cuts Nephropathy Risk in T2D

TOPLINE: Regular use of glucosamine, a widely used supplement to manage osteoarthritis and joint pain, was linked to reduced risks for both composite microvascular complications and diabetic nephropathy among patients with type 2 diabetes (T2D). METHODOLOGY: Glucosamine, used daily by about 20% of US and Australian adults to treat osteoarthritis and joint pain, has been … Read more

Semaglutide linked to higher risk of vision problems, FDA data analysis shows

Using real-world data from over 300,000 cases, scientists uncovered a significant link between semaglutide and reported vision problems—raising new concerns about the safety profile of this blockbuster medication. Study: Increased vision impairment reports linked to semaglutide: analysis of FDA adverse event data. Image Credit: memorisz / Shutterstock A team of researchers at the University of Bern, Switzerland, … Read more