Gut microbiome changes improve memory in early cognitive decline

From Mediterranean diets to probiotics, scientists reveal how reshaping the gut microbiome could help protect brain function, while highlighting why timing may be critical for slowing cognitive decline.  Study: The association between gut microbiota and cognitive decline: A systematic review of the literature. Image credit: Toa55/Shutterstock.com The gut-brain axis is gaining importance as a modulator … Read more

Multiple sclerosis prevalence in England doubles due to better diagnosis

Multiple sclerosis (MS) has more than doubled in recorded prevalence in England from 2000 to 2020, increasing by 6% per year, largely due to improved diagnosis and longer life expectancy, finds a new study by University College London (UCL) and Imperial College London researchers. The team found that survival of people with MS improved significantly … Read more

Menopause may raise women’s Alzheimer risk earlier than doctors once thought

A new review suggests the menopause transition may mark a critical window for Alzheimer’s prevention in women, shifting focus toward earlier detection, sex-specific risk factors, and more personalized care. Expert Review: Women’s midlife: the front line of Alzheimer prevention. Image Credit: izzuanroslan / Shutterstock In a recent review published in The Journal of Clinical Investigation, author … Read more

Viagra ingredient improves symptoms in patients with Leigh syndrome

Sildenafil – an active ingredient also marketed under the name of Viagra – improves symptoms in patients with Leigh syndrome. This has now been reported in the Cell journal by researchers at Charité – Universitätsmedizin Berlin, together with teams from Heinrich Heine University Düsseldorf (HHU), University Hospital Düsseldorf (UKD), and the Fraunhofer Institute for Translational Medicine … Read more

Study reveals why US life expectancy gains stalled after decades of progress

A sweeping cohort-based analysis of four decades of mortality data reveals how cardiovascular deaths, external causes, and generational health patterns are reshaping longevity in the United States. Study: Insights into US life expectancy stagnation from birth cohort mortality dynamics. Image Credit: tomertu / Shutterstock In a recent study published in the Proceedings of the National Academy … Read more

Brain injury protein in the blood could help estimate biological age in animals

The protein “neurofilament light chain” (NfL) – studied in humans in the context of neurodegenerative diseases and aging – is also detectable in the blood of numerous animals, and NfL levels increase with age in mice, cats, dogs, and horses. Experts from the DZNE and the Hertie Institute for Clinical Brain Research (HIH) at the … Read more

Cornell study finds existing drug could boost liver cancer immunotherapy

Immunotherapy – which activates the body’s own immune system to kill cancer cells – has not worked well against a rare and fatal liver cancer, but a new Cornell University study finds an existing FDA-approved drug may allow the immunotherapy to fight the cancer as intended, opening the door to a potential treatment. Fibrolamellar carcinoma … Read more

Healthy diets link to longer life regardless of longevity genes, large study finds

A major cohort study suggests that consistent adherence to established healthy eating patterns may add years to life, even after accounting for genetic predisposition. Study: Healthy dietary patterns, longevity genes, and life expectancy: A prospective cohort study. Image Credit: Pacorpi / Shutterstock In a recent study published in Science Advances, researchers investigated the impact of … Read more

Study reports life expectancies of spina bifida patients by age, sex, and severity of impairment

Studies have reported on survival probabilities of people born with open spina bifida, a condition where the spinal cord and nerves are exposed through an opening in the back. Research published in Developmental Medicine & Child Neurology now provides life expectancies, with results reported by age, sex, and different levels of impairment. In the study … Read more

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Researchers have found that prescribing guideline-directed medical treatment (GDMT), regardless of the number of medications, can improve survival rates in patients 90 years of age and older following their first heart attack, with the greatest benefit observed in patients who received all four recommended post-acute myocardial infarction (AMI) therapies. These include beta-blockers, antiplatelets, lipid-lowering drugs, … Read more