Colon

Upper gastrointestinal involvement is common in Egyptian patients with ulcerative colitis

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Background and objectives This study investigates upper gastrointestinal tract (UGIT) involvement in patients with ulcerative colitis (UC), a condition traditionally considered limited to the colon. Although extra-colonic manifestations of UC are well recognized, UGIT issues have received less attention. This research aimed to document the clinical, endoscopic, and histopathological UGIT findings in adults with UC … Read more

Friendly Viruses: How the Virom Benefits Your Health

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BUCHAREST – May 3, 2024 – Trillions of viruses, a hidden world within us, are now emerging as key players in our health, influencing our well-being from the gut to the brain. Scientists are uncovering the intricate roles viruses play in our bodies,not as illness-causing agents,but as silent,essential partners. These findings are opening new avenues … Read more

Comparing single cell RNA methods to improve gastrointestinal cancer research

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How would you summarize your study for a lay audience? Research on gastrointestinal diseases, especially cancer, has mainly looked at the epithelial cells, which line the surfaces of organs, are important for various functions, and are believed to be the cells that go awry to cause these diseases. However, studying these cells using single-cell RNA … Read more

Researchers analyze the mutational landscape of TMB-high colorectal cancer tumors

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Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide. The mutational landscape of CRC is well characterized, revealing key pathogenic genetic abnormalities that drive carcinogenesis (cancer development) and disease progression. Moreover, a step-wise colorectal carcinogenesis model has been proposed wherein … Read more

Moderate iron intake linked to lower colon cancer risk

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A new study reveals that moderate consumption of total and non-heme iron may reduce colorectal and colon cancer risk in South Korea, highlighting the role of plant-based iron in cancer prevention. Study: Iron Consumption and Colorectal Cancer in Korean Adults: A Prospective Cohort Study. Image Credit: Shutterstock AI Generator / Shutterstock.com A recent Nutrients study investigates the … Read more

High fiber diet helps protect against dangerous gut infections

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A study published in the journal Cell Host & Microbe by Brazilian and American researchers suggests that a diet rich in soluble fiber can protect the intestine against pathogenic bacteria. The conclusion is based on experiments with mice exposed to Clostridioides difficile, which causes colon inflammation and diarrhea and affects about 500,000 people a year in the United States. “We were able … Read more

Colorectal cancer burden climbs in countries with low milk intake

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Colorectal cancer cases are rising in low milk-consuming regions—this major global study reveals who’s most at risk and why the right amount of milk might matter more than you think. The ASR of deaths and DALYs attributable to diet low in milk for prostate cancer and colon and rectum cancer among countries and territories in … Read more

Researchers unlock key process for regenerating intestinal cells after injury

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Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. Peter Dempsey, PhD, professor of pediatrics–developmental biology in the CU School of Medicine, and Justin Brumbaugh, PhD, assistant professor of molecular, cellular, and developmental biology at CU Boulder, recently published a paper in the journal Nature Cell … Read more

Revolutionizing Cancer Treatment: The Power of Intestinal Bacteria as a New Ally

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Naples Leads Groundbreaking Melanoma Study: Could Gut Bacteria Be the Key to Better Immunotherapy? Naples, Italy, is at the forefront of a perhaps revolutionary melanoma study that could substantially improve cancer treatment outcomes. Researchers have identified specific types of intestinal bacteria that appear to enhance the effectiveness of immunotherapies in patients with advanced melanoma.This research, … Read more

AGA issues new recommendations on AI-assisted colonoscopy technology

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The American Gastroenterological Association (AGA) released a new clinical guideline making no recommendation – for or against – the use of computer-aided detection systems (CADe) in colonoscopy. A rigorous review of evidence showed that artificial intelligence-assisted technology helps identify colorectal polyps. However, its impact on preventing colorectal cancer – the third most common cancer worldwide … Read more