Review explores the underlying mechanisms of hepatocarcinogenesis post-HCV eradication

Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development. The introduction of direct-acting antivirals (DAAs) has revolutionized HCV treatment, achieving high rates of sustained virologic response (SVR) and reducing HCV-associated morbidity and mortality. Despite these advancements, the risk of HCC persists in … Read more

Immunising the elderly is crucial in disease prevention, say experts

The session was part of the ‘Healthy India, Happy India’ initiative aimed at promoting health and wellness | Image used for representational purpose only File | Photo Credit: Reuters Vaccination is a crucial yet often overlooked health measure for the elderly in India. Despite the absence of a dedicated national immunisation schedule for vaccinations among … Read more

Celiac Disease Linked to Persistent Risk for Liver Disease

TOPLINE: Patients with celiac disease have a twofold higher risk for developing any chronic liver disease than the general population, with the risk remaining elevated beyond 25 years after diagnosis. METHODOLOGY: A recent meta-analysis reported that approximately one fifth of patients with celiac disease have elevated aminotransferase levels, potentially signaling underlying liver injury or risk … Read more

Are we prepared for the next outbreak?

With over 600 known human viruses and new ones emerging, experts highlight how climate change, globalization, and zoonotic spillover are accelerating viral threats—are we ready for the next pandemic? Invited Review: Human viruses: An ever-increasing list. Image Credit: Lightspring / Shutterstock In a recent review published in the journal Virology, researchers examined the increasing diversity of human … Read more

How to prevent fatty liver disease, a silent killer, with minor lifestyle changes

Whether or not you attempted dry January by not drinking alcohol for the month, focusing on your liver could help safeguard your well-being. The liver is a vital organ that supports metabolism, immunity, digestion, detoxification and vitamin storage, among other functions. People are at a higher risk of developing fatty liver disease when they have … Read more

Yellow Fever Diagnostics in Laboratories

Yellow Fever in Diagnostic Laboratories Yellow fever is a serious viral infection that poses significant challenges for diagnostic laboratories. In a recent study published in Emerg Microbes Infect,… The post Yellow Fever Diagnostics in Laboratories appeared first on NewsyList. Source link

Revealing viral hepatitis epidemiology in the Democratic Republic of Congo: insights from yellow fever surveillance reanalysis | Tropical Medicine and Health

Domingo C, Charrel RN, Schmidt-Chanasit J, Zeller H, Reusken C. Yellow fever in the diagnostics laboratory. Emerg Microbes Infect. 2018;7(1):129. PubMed  PubMed Central  Google Scholar  World Health Organization. Yellow fever key facts: WHO; 2019 https://www.who.int/news-room/fact-sheets/detail/yellow-fever. Makiala-Mandanda S, Le Gal F, Ngwaka-Matsung N, Ahuka-Mundeke S, Onanga R, Bivigou-Mboumba B, et al. High prevalence and diversity of … Read more

New guidelines for hepatitis B virus reactivation management

New recommendations address advances in immunosuppressive therapies and highlight antiviral prophylaxis for high-risk patients. Study: AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals. Image Credit: Josep Suria / Shutterstock.com In a recent study published in Gastroenterology, researchers update clinical practice guidelines for how to prevent and monitor … Read more

Alcohol consumption increases risks of cirrhosis and HCC in patients with HBV infection

Background and aims The quantitative effects of alcohol consumption on cirrhosis and hepatocellular carcinoma (HCC) in hepatitis B virus (HBV) infection are unknown. This study aimed to establish a dose-dependent model of alcohol consumption on the risks of cirrhosis and HCC. Methods PubMed, Embase, the Cochrane Library, Web of Science, and four Chinese databases were … Read more

New research sheds light on changing liver cancer trends

Liver cancer is a leading cause of cancer-related deaths worldwide, with distinct geographic patterns in its incidence. In particular, China bears a disproportionate share of the global burden. The disease is strongly associated with chronic infections from hepatitis B and C, alcohol use, and increasingly, metabolic disorders like non-alcoholic fatty liver disease (NAFLD). As obesity … Read more