medicine

Researchers unlock key process for regenerating intestinal cells after injury

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Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. Peter Dempsey, PhD, professor of pediatrics–developmental biology in the CU School of Medicine, and Justin Brumbaugh, PhD, assistant professor of molecular, cellular, and developmental biology at CU Boulder, recently published a paper in the journal Nature Cell … Read more

Stanford study reveals glucose’s surprising role in cell differentiation

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The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation – the process by which stem cells give rise to specialized cells that make up all the body’s tissues. It does so not … Read more

Postpartum females show shift in temperature preferences due to brain changes

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Mothers experience major metabolic adaptations during pregnancy and lactation to support the development and growth of the new life. Although many metabolic changes have been studied, body temperature regulation and environmental temperature preference during and after pregnancy remain poorly understood. Researchers at Baylor College of Medicine and collaborating institutions show in the journal Molecular Metabolism … Read more

New open-source tool identifies aging cells to help fight chronic diseases

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For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer’s disease and other chronic diseases. But these cells are also like needles in a haystack, difficult to identify by traditional scientific measures.  To find these problematic cells, … Read more

HIF-PHIs May Offer Benefit over ESAs for Anemia With Dialysis-Dependent CKD

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Jyoti Tyagi, MPH Credit: Linkedin Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) seem to be a feasible alternative to erythropoietin-stimulating agents (ESA) for treating anemia in people with dialysis-dependent chronic kidney disease (DD-CKD), according to a new systematic review and meta-analysis.1 Specifically, daprodustat exhibited a substantial net benefit over ESAs in reducing the need for intravenous … Read more

Revolutionary AI Model Accurately Predicts Sepsis Mortality in ICU

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Archyde AI Revolutionizes sepsis Prediction in ICUs, Promising Improved Patient Outcomes Table of Contents 1. AI Revolutionizes sepsis Prediction in ICUs, Promising Improved Patient Outcomes 2. The Sepsis Crisis: A Race Against Time 3. A Breakthrough in Predictive Modeling: The Transformer-Based AI 4. How the AI Model Works: A Two-Pronged Approach 5. Identifying Key Predictors … Read more

New hepatitis B vaccine outperforms standard boosters in health care workers

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Background and goal: Health care workers are at higher risk of hepatitis B infection due to occupational exposure to blood and body fluids. They are considered protected if they have a hepatitis B surface antigen antibody (anti-HBs) titer of ≥10 mIU/mL after completing a full vaccination series. This study compared the effectiveness of Heplisav-B, a … Read more

New AI model predicts sepsis mortality in the ICU with high accuracy

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Sepsis is one of the deadliest conditions in intensive care units (ICUs), triggered by the body’s out-of-control response to infection. Despite medical advancements, its in-hospital mortality rate still hovers between 20% and 50%. The challenge lies in early identification—sepsis is highly dynamic, and current scoring systems like APACHE-II and SOFA are not specifically designed to … Read more

Family-based approach to lifestyle interventions reduces weight and cardiovascular risks

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Background and goal: The PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC) Study, conducted in India, aimed to assess whether a family-based approach to lifestyle interventions could improve weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease​. Study approach: In this cluster randomized controlled … Read more

Lifelong weight patterns linked to kidney cancer risk

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Excess weight in mid-life is a known risk factor for kidney cancer, but new research indicates that weight patterns throughout life may also affect an individual’s likelihood of developing this malignancy. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. To assess weight patterns and their associations … Read more