Adapting Diet to Chronotype Boosts Weight Loss, Gut Health

Among patients with overweight/obesity, a diet adapted to an individual’s chronotype was more effective in promoting weight loss and improving cardiometabolic health and gut microbiota (GM) than a conventional low-calorie diet. “Emerging evidence suggests that aligning dietary patterns with an individual’s circadian rhythm, or chronotype, may optimize metabolic processes and gut microbiota (GM) composition and … Read more

Bariatric Surgery Linked With Psoriasis Improvement

TOPLINE: Most patients with psoriasis experienced clinical improvement or remission after metabolic and bariatric surgery (MBS) in a systematic review. METHODOLOGY: Researchers conducted a systematic review of 14 studies that included 169 patients (mean age, 46.8 years; 74% women) with psoriasis who underwent MBS. Participants underwent various surgical procedures; gastric bypass was the most common … Read more

Consider Sex of Both Parent and Child in MetS Screening

TOPLINE: Parental metabolic syndrome (MetS) had a notable impact on the metabolic health of offspring; paternal MetS showed stronger associations with several metabolic markers in boys, whereas maternal MetS was linked to elevated triglyceride levels in both sexes but affected other markers, primarily in boys. METHODOLOGY: Multiple studies have examined the influence of parental MetS … Read more

Can Endocrine NP Training Help Ease Provider Shortage?

ORLANDO, Fla. — A program at Duke University School of Nursing, Durham, North Carolina, is currently one of just two in the United States that trains nurse practitioners (NPs) to provide endocrine specialty care, but more could be on the way. Established in 2016, the program was “a result of national demand for diabetes and … Read more

New Research: GLP-1 Receptor Agonists May Support Nicotine Cessation

Los Angeles — New research presented today at the American Psychiatric Association’s Annual Meeting shows that GLP-1 receptor agonists may be able to help cigarette smokers reduce weight gain while they are quitting. A team led by Debora Xavier, M.D., conducted a systematic review and meta-analysis to determine how abstinence from cigarettes and post-cessation weight … Read more

Dangerous Drug Interactions: A Quick Quiz

Prostate Cancer Treatment: Navigating Drug Interactions Bucharest – May 9, 2024 – Prostate cancer treatment involves careful management of drug interactions, as certain medications can pose risks when combined. This article explores the challenges of navigating these interactions,specifically concerning relugolix,a gonadotropin-releasing hormone antagonist. When is it a concern? Healthcare providers and patients must be aware … Read more

Metabolic Syndrome in Midlife Tied to Early-Onset Dementia

TOPLINE: Metabolic syndrome was associated with a 24% increased risk for young-onset dementia, defined as dementia before the age of 65 years, with stronger associations found in women vs men, younger vs older adults, and individuals with vs without depression, a new study showed. METHODOLOGY: This nationwide population-based cohort study included data from more than … Read more

Study Maps How Exosomes Hijack Blood Formation

TOPLINE: Chronic lymphocytic leukemia (CLL) cell–derived exosomes demonstrated the ability to alter healthy donor cell function and suppress normal blood cell formation. These particles affected monocytes, fibrocytes, and lymphocytes, leading to changes in gene expression and protein levels that may contribute to disease progression. METHODOLOGY: Researchers examined CLL cell–derived exosomes and their effects on healthy … Read more

Researchers Link Metabolic Age Clock and COPD

The same biological processes that drive aging — such as energy loss — may also contribute to lung diseases like chronic obstructive pulmonary disease (COPD).  Cleveland Clinic researchers have developed a metabolic age clock that evaluates an individual’s metabolic function relative to the expected norm for their age group. Using this tool, they identified a … Read more

Mediterranean Diet and Exercise Boost Bone Health in Seniors

TOPLINE: Compared with a conventional ad libitum Mediterranean diet, an energy-restricted Mediterranean diet along with physical activity helped preserve bone mineral density (BMD) during weight loss in older women with metabolic syndrome, showing the most benefits at the lumbar level over a 3-year period. METHODOLOGY: Individuals with obesity and older adults exhibit increased vulnerability to … Read more