Firmicutes bacteria can help maintain bone mass, study suggests

A recent study involving 684 Chinese adults has uncovered a significant connection between gut microbiota, aging, and bone health, particularly in relation to osteoporosis, a condition that weakens bones and increases the risk of fractures. The research, conducted by BGI Genomics’ Institute of Intelligent Medical Research (IIMR) and partner institutions, was published in npj | Metabolic Health and Disease, an … Read more

NELL2 identified as a key regulator of bone formation and fat suppression

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes osteoblast differentiation and inhibits adipocyte formation in bone marrow stromal cells, addressing the bone remodeling imbalance in osteoporosis. The study further uncovers the molecular mechanism of NELL2’s action, revealing … Read more

Diet and exercise habits in your 60s linked to lower fracture and heart death ris

A 20-year UK study reveals that simple dietary shifts can lower fracture and cardiovascular risks—offering a compelling case for lifestyle change, especially in men. Study: 60 is the new 40: preparing for better bone health in later life. Image Credit: Umomos / Shutterstock In a recent study published in the journal Frontiers in Aging, researchers at the … Read more

Colorectal cancer burden climbs in countries with low milk intake

Colorectal cancer cases are rising in low milk-consuming regions—this major global study reveals who’s most at risk and why the right amount of milk might matter more than you think. The ASR of deaths and DALYs attributable to diet low in milk for prostate cancer and colon and rectum cancer among countries and territories in … Read more

Young men with late puberty have healthier fat-to-muscle ratios

Young men who hit puberty later have lower bone mass but healthier fat-to-muscle ratios, suggesting that delayed maturation may offer long-term body composition benefits. Study: Association between pubertal timing and bone and body composition in young adult men. Image Credit: Lapina / Shutterstock In a recent study published in the journal Scientific Reports, researchers examined how the … Read more

Study highlights disparities in osteoporosis diagnosis across demographics

While increased average life expectancy is a testament to modern medicine and public health efforts, an aging population comes with an increased presence of chronic diseases such as osteoporosis. Research published in Osteoporosis International by Hong Xue and graduate students Christopher Naso, Ge Song, and Kenny Lin supplies evidence that some groups are at greater risk for osteoporosis and … Read more

Can yogurt and kefir help prevent osteoporosis? Scientists examine the facts

Scientists investigate whether fermented dairy and probiotics can help prevent osteoporosis—do they hold the key to stronger bones or is the science still uncertain? Review: The Impact of Fermented Dairy Products and Probiotics on Bone Health Improvement. Image Credit: Crevis / Shutterstock A recent review in the Food Science of Animal Resources journal highlights the importance of … Read more

Common Drug Could Counter a Rare Type of Heart Disease

Scientists at the University of Arizona found that the osteoporosis drug risedronate may help treat a rare genetic mutation linked to dilated cardiomyopathy (DCM), a heart disease affecting younger individuals. Using AI and supercomputers, they identified and tested the drug, which successfully corrected the mutated protein in animal models, paving the way for clinical trials. … Read more

FDA-approved osteoporosis drug may treat rare genetic heart disease

A research team co-led by scientists at the University of Arizona College of Medicine – Tucson found that an osteoporosis drug might counter a rare genetic mutation underlying a type of heart disease. The results were published today in the Journal of Clinical Investigation and could have implications for treating other rare diseases. Dilated cardiomyopathy is a group of … Read more